Literature DB >> 22075925

Primary percutaneous coronary intervention as a national reperfusion strategy in patients with ST-segment elevation myocardial infarction.

Christian J Terkelsen1, Lisette O Jensen, Hans H Tilsted, Per Thaysen, Jan Ravkilde, Søren P Johnsen, Sven Trautner, Henning R Andersen, Leif Thuesen, Jens F Lassen.   

Abstract

BACKGROUND: In Denmark, primary percutaneous coronary intervention (PPCI) was chosen as a national reperfusion strategy for patients with ST-segment elevation myocardial infarction in 2003. This study describes the temporal implementation of PPCI in Western Denmark, the gradual introduction of field triage for PPCI (patients rerouted from the scene of the event directly to the invasive center), and the associated outcome. METHODS AND
RESULTS: The study population comprised 9514 patients treated with PPCI from 1999 to 2009 with symptom duration ≤12 hours and either a delay from the emergency medical service (EMS) call to PPCI (healthcare system delay) of ≤6 hours or as self-presenters. The median follow-up time was 3.7 years. The number of patients treated with PPCI increased from 190 in 1999 to 1212 in 2009. Among patients transported by the EMS from the scene of the event, the proportion who were field triaged directly to a PCI center increased from 33% (34/103) to 72% (616/851, P<0.001). Patients who were field triaged had lower long-term mortality, with adjusted hazard ratios (95% CI) of 1.26 (1.12-1.43) among patients transported by the EMS to a local hospital and then transferred, 1.28 (1.10-1.49) among patients self-presenting at a local hospital and then transferred, and 1.37 (1.18-1.58) among patients self-presenting at a PCI center.
CONCLUSIONS: A reperfusion strategy with PPCI only for patients with ST-segment elevation myocardial infarction was successfully implemented in Western Denmark, and the majority of patients transported by the EMS are now triaged directly to the PPCI centers. This strategy is associated with lower mortality.

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Year:  2011        PMID: 22075925     DOI: 10.1161/CIRCINTERVENTIONS.111.962787

Source DB:  PubMed          Journal:  Circ Cardiovasc Interv        ISSN: 1941-7640            Impact factor:   6.546


  10 in total

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Authors:  Harold L Dauerman; Burton E Sobel
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Review 2.  Timely and optimal treatment of patients with STEMI.

Authors:  Jens F Lassen; Hans E Bøtker; Christian J Terkelsen
Journal:  Nat Rev Cardiol       Date:  2012-11-20       Impact factor: 32.419

3.  Time to treatment-door-to-balloon time is not everything.

Authors:  C J Terkelsen
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Review 4.  Role of nitric oxide in the functional response to ischemia-reperfusion of heart mitochondria from hyperthyroid rats.

Authors:  P Venditti; R De Rosa; L Cigliano; C Agnisola; S Di Meo
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5.  Reperfusion delay in patients treated with primary percutaneous coronary intervention: insight from a real world Danish ST-segment elevation myocardial infarction population in the era of telemedicine.

Authors:  Mikkel M Schoos; Maria Sejersten; Anders Hvelplund; Mette Madsen; Jacob Lønborg; Jacob Steinmetz; Philip M Treschow; Frants Pedersen; Erik Jørgensen; Peer Grande; Henning Kelbæk; Peter Clemmensen
Journal:  Eur Heart J Acute Cardiovasc Care       Date:  2012-09

6.  Strategies TO reduce time delays in patients with AcuTe coronary heart disease treated with primary PCI--the STOP WATCH study: a multistage action research project.

Authors:  Tim Tödt; Ingela Thylén; Joakim Alfredsson; Eva Swahn; Magnus Janzon
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Review 7.  The impact of direct admission to a catheterisation lab/CCU in patients with ST-elevation myocardial infarction on the delay to reperfusion and early risk of death: results of a systematic review including meta-analysis.

Authors:  Magnus Andersson Hagiwara; Anders Bremer; Andreas Claesson; Christer Axelsson; Gabriella Norberg; Johan Herlitz
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2014-11-25       Impact factor: 2.953

8.  Dyspnea, a high-risk symptom in patients suspected of myocardial infarction in the ambulance? A population-based follow-up study.

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Journal:  Scand J Trauma Resusc Emerg Med       Date:  2016-02-12       Impact factor: 2.953

9.  A simple score for the prediction of stent thrombosis in patients with ST elevation myocardial infarction: TIMI risk index.

Authors:  Tufan Çınar; Yavuz Karabağ; Cengiz Burak; Veysel Ozan Tanık; Mahmut Yesin; Metin Çağdaş; İbrahim Rencüzoğulları
Journal:  J Cardiovasc Thorac Res       Date:  2019-08-07

10.  Cardiac Myosin-Binding Protein C to Diagnose Acute Myocardial Infarction in the Pre-Hospital Setting.

Authors:  Thomas E Kaier; Carsten Stengaard; Jack Marjot; Jacob Thorsted Sørensen; Bashir Alaour; Stavroula Stavropoulou-Tatla; Christian Juhl Terkelsen; Luke Williams; Kristian Thygesen; Ekkehard Weber; Michael Marber; Hans Erik Bøtker
Journal:  J Am Heart Assoc       Date:  2019-07-26       Impact factor: 5.501

  10 in total

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