| Literature DB >> 2207135 |
M R Adhin1, A Avots, V Berzin, G P Overbeek, J van Duin.
Abstract
We report the complete nucleotide sequence of the group I RNA bacteriophage fr. The entire genome consists of 3575 nucleotides, six nucleotides more than the only other sequenced group I representative, MS2. The greatest divergence between these phages occurs in the 5' terminal region of the A gene, while the lysis-replicase gene overlap, the coat gene and the central region of the replicase gene are highly conserved. Overall sequence homology between fr and MS2 is 77%. Here, we present a general comparison between the two phages. In the accompanying paper we use phylogenetic sequence comparison between MS2 and fr to deduce the secondary structure at the 3' untranslated region.Entities:
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Year: 1990 PMID： 2207135 DOI： 10.1016/0167-4781(90)90149-v
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002