Literature DB >> 22070138

Catalyst-free preparation of 1,2,4,5-tetrasubstituted imidazoles from a novel unexpected domino reaction of 2-azido acrylates and nitrones.

Bao Hu1, Zhao Wang, Ning Ai, Jie Zheng, Xing-Hai Liu, Shang Shan, Zhongwen Wang.   

Abstract

A highly efficient and convenient method for the synthesis of 1,2,4,5-tetrasubstituted imidazoles from readily accessible 2-azido acrylates and nitrones has been developed. This reaction proceeded under mild conditions without the assistance of any metal, acid, or base.

Entities:  

Year:  2011        PMID： 22070138     DOI： 10.1021/ol202650z

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  8 in total

Review 1.  Transition metal-free one-pot synthesis of nitrogen-containing heterocycles.

Authors:  Simpal Kumari; Dharma Kishore; Sarvesh Paliwal; Rajani Chauhan; Jaya Dwivedi; Aakanksha Mishra
Journal:  Mol Divers       Date:  2015-06-09       Impact factor: 2.943

Review 2.  Reactivities of vinyl azides and their recent applications in nitrogen heterocycle synthesis.

Authors:  Bao Hu; Stephen G DiMagno
Journal:  Org Biomol Chem       Date:  2015-04-07       Impact factor: 3.876

3.  Mechanistic Pathways in Amide Activation: Flexible Synthesis of Oxazoles and Imidazoles.

Authors:  Giovanni Di Mauro; Boris Maryasin; Daniel Kaiser; Saad Shaaban; Leticia González; Nuno Maulide
Journal:  Org Lett       Date:  2017-07-13       Impact factor: 6.005

Review 4.  Vinylazides: versatile synthons and magical precursors for the construction of N-heterocycles.

Authors:  Zahra Tashrifi; Mohammad Mohammadi-Khanaposhtani; Bagher Larijani; Halleh Hamedifar; Samira Ansari; Mohammad Mahdavi
Journal:  Mol Divers       Date:  2020-05-30       Impact factor: 2.943

5.  A palladium-catalyzed synthesis of (hetero)aryl-substituted imidazoles from aryl halides, imines and carbon monoxide.

Authors:  Jevgenijs Tjutrins; Bruce A Arndtsen
Journal:  Chem Sci       Date:  2016-11-03       Impact factor: 9.825

6.  An efficient and targeted synthetic approach towards new highly substituted 6-amino-pyrazolo[1,5-a]pyrimidines with α-glucosidase inhibitory activity.

Authors:  Fariba Peytam; Mehdi Adib; Reihaneh Shourgeshty; Loghman Firoozpour; Mahmoud Rahmanian-Jazi; Mehdi Jahani; Setareh Moghimi; Kouros Divsalar; Mohammad Ali Faramarzi; Somayeh Mojtabavi; Fatemeh Safari; Mohammad Mahdavi; Alireza Foroumadi
Journal:  Sci Rep       Date:  2020-02-13       Impact factor: 4.379

7.  One-Step Synthesis of 2,5-Diaminoimidazoles and Total Synthesis of Methylglyoxal-Derived Imidazolium Crosslink (MODIC).

Authors:  Venkata R Sabbasani; Kung-Pern Wang; Matthew D Streeter; David A Spiegel
Journal:  Angew Chem Int Ed Engl       Date:  2019-11-12       Impact factor: 15.336

8.  Design, synthesis, molecular docking, and in vitro α-glucosidase inhibitory activities of novel 3-amino-2,4-diarylbenzo[4,5]imidazo[1,2-a]pyrimidines against yeast and rat α-glucosidase.

Authors:  Fariba Peytam; Ghazaleh Takalloobanafshi; Toktam Saadattalab; Maryam Norouzbahari; Zahra Emamgholipour; Setareh Moghimi; Loghman Firoozpour; Hamid Reza Bijanzadeh; Mohammad Ali Faramarzi; Somayeh Mojtabavi; Parviz Rashidi-Ranjbar; Saeed Karima; Roya Pakraad; Alireza Foroumadi
Journal:  Sci Rep       Date:  2021-06-07       Impact factor: 4.379
  8 in total

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