Literature DB >> 22064945

Polyaspartic acid coated manganese oxide nanoparticles for efficient liver MRI.

Ruijun Xing1, Fan Zhang, Jin Xie, Maria Aronova, Guofeng Zhang, Ning Guo, Xinglu Huang, Xiaolian Sun, Gang Liu, L Henry Bryant, Ashwinkumar Bhirde, Amy Liang, Yanglong Hou, Richard D Leapman, Shouheng Sun, Xiaoyuan Chen.   

Abstract

We report in this communication a simple, facile surface modification strategy to transfer hydrophobic manganese oxide nanoparticles (MONPs) into water by using polyaspartic acid (PASP). We systematically investigated the effect of the size of PASP-MONPs on MRI of normal liver and found that the particles with a core size of 10 nm exhibited greater enhancement than those with larger core sizes.

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Year:  2011        PMID： 22064945      PMCID： PMC3617494          DOI： 10.1039/c1nr11242b

Source DB:  PubMed          Journal:  Nanoscale        ISSN： 2040-3364            Impact factor:   7.790


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