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Literature DB >> 20730157

HSA coated MnO nanoparticles with prominent MRI contrast for tumor imaging.

Jing Huang¹, Jin Xie, Kai Chen, Lihong Bu, Seulki Lee, Zhen Cheng, Xingguo Li, Xiaoyuan Chen.

Abstract

We report in this Communication a facile, two-step surface modification strategy to achieve manganese oxide nanoparticles with prominent MRI T1 contrast. In a U87MG glioblastoma xenograft model, we confirmed that the particles can accumulate efficiently in tumor area to induce effective T1 signal alteration.

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Year: 2010 PMID： 20730157 PMCID： PMC3629962 DOI： 10.1039/c0cc01041c

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

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