Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Dual anticancer activity in a single compound: visible-light-induced apoptosis by an antiangiogenic iridium complex.

Literature DB >> 22057186

Dual anticancer activity in a single compound: visible-light-induced apoptosis by an antiangiogenic iridium complex.

Anja Kastl¹, Alexander Wilbuer, Anna Lena Merkel, Li Feng, Pietro Di Fazio, Matthias Ocker, Eric Meggers.

Abstract

A metal complex is identified in which the metal fulfills two independent functions: as a structural scaffold for the specific molecular recognition of protein kinases resulting in antiangiogenic properties, together with a visible-light-induced photoreactivity triggering apopotosis in cancer cells. This journal is © The Royal Society of Chemistry 2012

Entities: Chemical Disease

Mesh：

Substances：

Year: 2011 PMID： 22057186 DOI： 10.1039/c1cc15378a

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

Keyword Cloud
Cited

15 in total

1. Assessing the intracellular fate of rhodium(ii) complexes.

Authors: Matthew B Minus; Marci K Kang; Sarah E Knudsen; Wei Liu; Michael J Krueger; Morgen L Smith; Michele S Redell; Zachary T Ball
Journal: Chem Commun (Camb) Date: 2016-09-22 Impact factor: 6.222

2. Novel Quinoline-based Ir(III) Complexes Exhibit High Antitumor Activity in Vitro and in Vivo.

Authors: Yan Yang; Yi-Dong Bin; Qi-Pin Qin; Xu-Jian Luo; Bi-Qun Zou; Hua-Xin Zhang
Journal: ACS Med Chem Lett Date: 2019-11-06 Impact factor: 4.345

3. Polymeric Micelle-Mediated Delivery of DNA-Targeting Organometallic Complexes for Resistant Ovarian Cancer Treatment.

Authors: Xiaopin Duan; Demin Liu; Christina Chan; Wenbin Lin
Journal: Small Date: 2015-05-12 Impact factor: 13.281

4. Organometallic Palladium Complexes with a Water-Soluble Iminophosphorane Ligand as Potential Anticancer Agents.

Authors: Monica Carreira; Rubén Calvo-Sanjuán; Mercedes Sanaú; Isabel Marzo; María Contel
Journal: Organometallics Date: 2012-07-25 Impact factor: 3.876

5. Rhenium Complexes with Red-Light-Induced Anticancer Activity.

Authors: Kathrin Wähler; Anja Ludewig; Patrick Szabo; Klaus Harms; Eric Meggers
Journal: Eur J Inorg Chem Date: 2014-02-01 Impact factor: 2.524

6. Rhenium complexes with visible-light-induced anticancer activity.

Authors: Anja Kastl; Sandra Dieckmann; Kathrin Wähler; Timo Völker; Lena Kastl; Anna Lena Merkel; Adina Vultur; Batool Shannan; Klaus Harms; Matthias Ocker; Wolfgang J Parak; Meenhard Herlyn; Eric Meggers
Journal: ChemMedChem Date: 2013-04-08 Impact factor: 3.466

Dual anticancer activity in a single compound: visible-light-induced apoptosis by an antiangiogenic iridium complex.

1. Assessing the intracellular fate of rhodium(ii) complexes.

2. Novel Quinoline-based Ir(III) Complexes Exhibit High Antitumor Activity in Vitro and in Vivo.

3. Polymeric Micelle-Mediated Delivery of DNA-Targeting Organometallic Complexes for Resistant Ovarian Cancer Treatment.

4. Organometallic Palladium Complexes with a Water-Soluble Iminophosphorane Ligand as Potential Anticancer Agents.

5. Rhenium Complexes with Red-Light-Induced Anticancer Activity.

6. Rhenium complexes with visible-light-induced anticancer activity.

7. Ligand-Controlled Reactivity and Cytotoxicity of Cyclometalated Rhodium(III) Complexes.

8. Reduction of quinones by NADH catalyzed by organoiridium complexes.

9. A metal-based inhibitor of NEDD8-activating enzyme.

Review 10. Organoiridium complexes: anticancer agents and catalysts.