A A Chantry1, E Lopez. 1. Inserm, UMR 953, recherche épidémiologique en santé périnatale, santé des femmes et des enfants, 75020 Paris, France.
Abstract
OBJECTIVE: To evaluate fetal and neonatal outcomes related to prolonged pregnancy. METHODS: This study is based on Pubmed search, Cochrane library and HAS recommendations. RESULTS: The risk of fetal complications including macrosomia (6 %), oligohydramnios (10 %-15 %), abnormal fetal heart rate pattern and meconium-stained fluid is increased in prolonged pregnancy (≥ 41(+0) weeks). The rate of stillbirth was estimated between 1.6 ‰ and 3.0 ‰ live births according to countries in post-term pregnancies (≥ 42(+0) weeks). The risk of umbilical cord pH less than 7.10, Apgar score at five minutes inferior to 7, ICU admissions and perinatal asphyxia is increased in post-term infants (≥ 42(+0) weeks) compared with term infants. The risk of neurologic complications including neonatal convulsion, hypoxic ischemic encephalopathy, cerebral palsy, developmental deviations and epilepsy in childhood is increased in post-term infants. The risk of meconium aspiration syndrome, neonatal sepsis, and birth trauma including shoulder dystocia and bone fracture is increased in post-term infants. The rate of perinatal mortality increases in post-term infants. The perinatal mortality in post-term infants could be explained by perinatal asphyxia and meconium aspiration syndrome. CONCLUSIONS: The risk of perinatal complications and mortality are increased in prolonged pregnancy.
OBJECTIVE: To evaluate fetal and neonatal outcomes related to prolonged pregnancy. METHODS: This study is based on Pubmed search, Cochrane library and HAS recommendations. RESULTS: The risk of fetal complications including macrosomia (6 %), oligohydramnios (10 %-15 %), abnormal fetal heart rate pattern and meconium-stained fluid is increased in prolonged pregnancy (≥ 41(+0) weeks). The rate of stillbirth was estimated between 1.6 ‰ and 3.0 ‰ live births according to countries in post-term pregnancies (≥ 42(+0) weeks). The risk of umbilical cord pH less than 7.10, Apgar score at five minutes inferior to 7, ICU admissions and perinatal asphyxia is increased in post-term infants (≥ 42(+0) weeks) compared with term infants. The risk of neurologic complications including neonatal convulsion, hypoxic ischemic encephalopathy, cerebral palsy, developmental deviations and epilepsy in childhood is increased in post-term infants. The risk of meconium aspiration syndrome, neonatal sepsis, and birth trauma including shoulder dystocia and bone fracture is increased in post-term infants. The rate of perinatal mortality increases in post-term infants. The perinatal mortality in post-term infants could be explained by perinatal asphyxia and meconium aspiration syndrome. CONCLUSIONS: The risk of perinatal complications and mortality are increased in prolonged pregnancy.
Authors: John Mark P Pabona; Daying Zhang; David S Ginsburg; Frank A Simmen; Rosalia C M Simmen Journal: J Clin Endocrinol Metab Date: 2015-01 Impact factor: 5.958
Authors: Joep C Kortekaas; Aafke Bruinsma; Judit K J Keulen; Jeroen van Dillen; Martijn A Oudijk; Joost J Zwart; Jannet J H Bakker; Dokie de Bont; Marianne Nieuwenhuijze; Pien M Offerhaus; Anton H van Kaam; Frank Vandenbussche; Ben Willem J Mol; Esteriek de Miranda Journal: BMC Pregnancy Childbirth Date: 2014-10-23 Impact factor: 3.007