| Literature DB >> 22054142 |
Gayathri K Perera1, Paola Di Meglio, Frank O Nestle.
Abstract
Psoriasis is a common relapsing and remitting immune-mediated inflammatory disease that affects the skin and joints. This review focuses on current immunogenetic concepts, key cellular players, and axes of cytokines that are thought to contribute to disease pathogenesis. We highlight potential therapeutic targets and give an overview of the currently used immune-targeted therapies.Entities:
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Year: 2011 PMID: 22054142 DOI: 10.1146/annurev-pathol-011811-132448
Source DB: PubMed Journal: Annu Rev Pathol ISSN: 1553-4006 Impact factor: 23.472