AIMS: Vertebral bone marrow is a rich and easily accessible source of hematopoietic and mesenchymal stem cells that has been used to promote chimerism and transplantation tolerance in connection with cadaveric organ transplantation. The purpose of this study is to provide a detailed account of the procedure used to prepare the first five vertebral bone marrow products for infusion in conjunction with the first hand/hand-forelimb transplants performed at the University of Pittsburgh (PA, USA). MATERIALS & METHODS: The cell separation and release testing were performed at the University of Pittsburgh Cancer Institute's Hematopoietic Stem Cell Laboratory, a Good Manufacturing Practice-compliant facility accredited for clinical cell processing by the Foundation for Accreditation of Cellular Therapy (FACT) and for clinical flow cytometry by the College of American Pathologists (CAP).
AIMS: Vertebral bone marrow is a rich and easily accessible source of hematopoietic and mesenchymal stem cells that has been used to promote chimerism and transplantation tolerance in connection with cadaveric organ transplantation. The purpose of this study is to provide a detailed account of the procedure used to prepare the first five vertebral bone marrow products for infusion in conjunction with the first hand/hand-forelimb transplants performed at the University of Pittsburgh (PA, USA). MATERIALS & METHODS: The cell separation and release testing were performed at the University of Pittsburgh Cancer Institute's Hematopoietic Stem Cell Laboratory, a Good Manufacturing Practice-compliant facility accredited for clinical cell processing by the Foundation for Accreditation of Cellular Therapy (FACT) and for clinical flow cytometry by the College of American Pathologists (CAP).
Authors: A D Donnenberg; E K Koch; D L Griffin; H M Stanczak; J E Kiss; T M Carlos; D M Buchbarker; A M Yeager Journal: Cytotherapy Date: 2002 Impact factor: 5.414
Authors: Kodi K Azari; Joseph E Imbriglia; Robert J Goitz; Jaimie T Shores; Marshall L Balk; Gerald Brandacher; Stephan Schneeberger; Vijay Gorantla; W P Andrew Lee Journal: J Reconstr Microsurg Date: 2011-08-02 Impact factor: 2.873
Authors: A S Rao; D Phil; P Fontes; A Iyengar; A Aitouche; R Shapiro; A Zeevi; F Dodson; R Corry; C Rastellini; J J Fung; T E Starzl Journal: Adv Exp Med Biol Date: 1997 Impact factor: 2.622
Authors: A S Rao; P Fontes; A Zeevi; M Trucco; R Shapiro; A J Demetris; A G Tzakis; P B Carroll; W A Rudert; F S Dodson Journal: Transplant Proc Date: 1994-12 Impact factor: 1.066
Authors: Maria T Millan; Judith A Shizuru; Petra Hoffmann; Sussan Dejbakhsh-Jones; John D Scandling; F Carl Grumet; Jane C Tan; Oscar Salvatierra; Richard T Hoppe; Samuel Strober Journal: Transplantation Date: 2002-05-15 Impact factor: 4.939
Authors: S M Pham; R J Keenan; A S Rao; P A Fontes; R L Kormos; K Abu-Elmagd; A Zeevi; A Kawai; B G Hattler; R L Hardesty Journal: Ann Thorac Surg Date: 1995-10 Impact factor: 4.330
Authors: P Fontes; A S Rao; A J Demetris; A Zeevi; M Trucco; P Carroll; W Rybka; W A Rudert; C Ricordi; F Dodson Journal: Lancet Date: 1994-07-16 Impact factor: 79.321
Authors: Erika Moravcikova; E Michael Meyer; Mirko Corselli; Vera S Donnenberg; Albert D Donnenberg Journal: Cytometry A Date: 2018-09-13 Impact factor: 4.355
Authors: Stefan Schneeberger; Vijay S Gorantla; Gerald Brandacher; Adriana Zeevi; Anthony J Demetris; John G Lunz; Diana M Metes; Albert D Donnenberg; Jaimie T Shores; Andrea F Dimartini; Joseph E Kiss; Joseph E Imbriglia; Kodi Azari; Robert J Goitz; Ernest K Manders; Vu T Nguyen; Damon S Cooney; Galen S Wachtman; Jonathan D Keith; Derek R Fletcher; Camila Macedo; Raymond Planinsic; Joseph E Losee; Ron Shapiro; Thomas E Starzl; W P Andrew Lee Journal: Ann Surg Date: 2013-02 Impact factor: 12.969
Authors: Martha L Bustos; Luai Huleihel; Ernest M Meyer; Albert D Donnenberg; Vera S Donnenberg; Joseph D Sciurba; Lyle Mroz; Bryan J McVerry; Bryon M Ellis; Naftali Kaminski; Mauricio Rojas Journal: Stem Cells Transl Med Date: 2013-10-02 Impact factor: 6.940
Authors: Erik J Woods; Aubrey M Sherry; John R Woods; James W Hardin; Michael LaFontaine; Gerald Brandacher; Brian H Johnstone Journal: J Transl Med Date: 2020-08-05 Impact factor: 5.531
Authors: Brian H Johnstone; Hannah M Miller; Madelyn R Beck; Dongsheng Gu; Sreedhar Thirumala; Michael LaFontaine; Gerald Brandacher; Erik J Woods Journal: Cytotherapy Date: 2020-08-30 Impact factor: 5.414