Literature DB >> 22042207

A novel fluorescent probe for NAD-consuming enzymes.

Giulia Pergolizzi1, Julea N Butt, Richard P Bowater, Gerd K Wagner.   

Abstract

A novel, fluorescent NAD derivative is processed as substrate by three different NAD-consuming enzymes. The new probe has been used to monitor enzymatic activity in a continuous format by changes in fluorescence and, in one case, to directly visualize alternative reaction pathways.

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Year:  2011        PMID: 22042207     DOI: 10.1039/c1cc15499k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  8 in total

1.  Emissive Synthetic Cofactors: Enzymatic Interconversions of tz A Analogues of ATP, NAD+ , NADH, NADP+ , and NADPH.

Authors:  François Hallé; Andrea Fin; Alexander R Rovira; Yitzhak Tor
Journal:  Angew Chem Int Ed Engl       Date:  2017-12-21       Impact factor: 15.336

2.  Emissive Synthetic Cofactors: An Isomorphic, Isofunctional, and Responsive NAD+ Analogue.

Authors:  Alexander R Rovira; Andrea Fin; Yitzhak Tor
Journal:  J Am Chem Soc       Date:  2017-10-27       Impact factor: 15.419

3.  Biochemical and Structural Characterisation of DNA Ligases from Bacteria and Archaea.

Authors:  Giulia Pergolizzi; Gerd K Wagner; Richard Peter Bowater
Journal:  Biosci Rep       Date:  2016-10-06       Impact factor: 3.840

4.  Crystal structure and functional implication of bacterial STING.

Authors:  Tzu-Ping Ko; Yu-Chuan Wang; Chia-Shin Yang; Mei-Hui Hou; Chao-Jung Chen; Yi-Fang Chiu; Yeh Chen
Journal:  Nat Commun       Date:  2022-01-10       Impact factor: 14.919

Review 5.  Functionalised Cofactor Mimics for Interactome Discovery and Beyond.

Authors:  Isabel V L Wilkinson; Martin Pfanzelt; Stephan A Sieber
Journal:  Angew Chem Int Ed Engl       Date:  2022-05-31       Impact factor: 16.823

6.  Initial Kinetic Characterization of Sterile Alpha and Toll/Interleukin Receptor Motif-Containing Protein 1.

Authors:  Heather S Loring; Janneke D Icso; Venkatesh V Nemmara; Paul R Thompson
Journal:  Biochemistry       Date:  2020-02-17       Impact factor: 3.162

7.  A Novel NAD-RNA Decapping Pathway Discovered by Synthetic Light-Up NAD-RNAs.

Authors:  Florian Abele; Katharina Höfer; Patrick Bernhard; Julia Grawenhoff; Maximilian Seidel; André Krause; Sara Kopf; Martin Schröter; Andres Jäschke
Journal:  Biomolecules       Date:  2020-03-28

Review 8.  NAD Analogs in Aid of Chemical Biology and Medicinal Chemistry.

Authors:  Anais Depaix; Joanna Kowalska
Journal:  Molecules       Date:  2019-11-19       Impact factor: 4.411

  8 in total

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