Literature DB >> 2204153

Why are proteins O-glycosylated?

N Jentoft1.   

Abstract

The O-linked oligosaccharides of glycoproteins are usually clustered within heavily glycosylated regions of the peptide chain. Steric interactions between carbohydrate and peptide within these clusters induce the peptide core to adopt a stiff and extended conformation and this conformational effect appears to represent a major function of O-glycosylation.

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Year:  1990        PMID： 2204153     DOI： 10.1016/0968-0004(90)90014-3

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  177 in total

1.  Cloning and characterization of gp36, a human mucin-type glycoprotein preferentially expressed in vascular endothelium.

Authors:  G Zimmer; F Oeffner; V Von Messling; T Tschernig; H J Gröness; H D Klenk; G Herrler
Journal:  Biochem J       Date:  1999-07-15       Impact factor: 3.857

2.  Complete sequence of the human mucin MUC4: a putative cell membrane-associated mucin.

Authors:  N Moniaux; S Nollet; N Porchet; P Degand; A Laine; J P Aubert
Journal:  Biochem J       Date:  1999-03-01       Impact factor: 3.857

Review 3.  Progress in molecular and genetic studies of IgA nephropathy.

Authors:  J Novak; B A Julian; M Tomana; J Mesteck
Journal:  J Clin Immunol       Date:  2001-09       Impact factor: 8.317

Review 4.  Mucins and blastocyst attachment.

Authors:  Amantha Thathiah; Daniel D Carson
Journal:  Rev Endocr Metab Disord       Date:  2002-05       Impact factor: 6.514

5.  Role of Fig2p in agglutination in Saccharomyces cerevisiae.

Authors:  Chong K Jue; Peter N Lipke
Journal:  Eukaryot Cell       Date:  2002-10

6.  Complement regulation at the molecular level: the structure of decay-accelerating factor.

Authors:  P Lukacik; P Roversi; J White; D Esser; G P Smith; J Billington; P A Williams; P M Rudd; M R Wormald; D J Harvey; M D M Crispin; C M Radcliffe; R A Dwek; D J Evans; B P Morgan; R A G Smith; S M Lea
Journal:  Proc Natl Acad Sci U S A       Date:  2004-01-20       Impact factor: 11.205

7.  Molecular cloning of amphiglycan, a novel integral membrane heparan sulfate proteoglycan expressed by epithelial and fibroblastic cells.

Authors:  G David; B van der Schueren; P Marynen; J J Cassiman; H van den Berghe
Journal:  J Cell Biol       Date:  1992-08       Impact factor: 10.539

Review 8.  Role of intestinal mucins in innate host defense mechanisms against pathogens.

Authors:  Poonam Dharmani; Vikas Srivastava; Vanessa Kissoon-Singh; Kris Chadee
Journal:  J Innate Immun       Date:  2008-10-08       Impact factor: 7.349

Review 9.  Glycobiology of the ocular surface: mucins and lectins.

Authors:  Pablo Argüeso
Journal:  Jpn J Ophthalmol       Date:  2013-01-17       Impact factor: 2.447

10.  Characterization of porcine intestinal receptors for the K88ac fimbrial adhesin of Escherichia coli as mucin-type sialoglycoproteins.

Authors:  A K Erickson; D R Baker; B T Bosworth; T A Casey; D A Benfield; D H Francis
Journal:  Infect Immun       Date:  1994-12       Impact factor: 3.441
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