Literature DB >> 12455701

Role of Fig2p in agglutination in Saccharomyces cerevisiae.

Chong K Jue1, Peter N Lipke.   

Abstract

In W303-derived strains, disruption of FIG2 increased agglutinability of alpha cells, but not a cells, and did not alter expression of alpha-agglutinin, binding of 125I-labeled alpha-agglutinin, or mating efficiency. Fig2p overexpression led to alpha-cell-specfic suppression of agglutinability. These results imply that Fig2p is an indirect masker of the active sites in alpha-agglutinin.

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Year:  2002        PMID: 12455701      PMCID: PMC126741          DOI: 10.1128/EC.1.5.843-845.2002

Source DB:  PubMed          Journal:  Eukaryot Cell        ISSN: 1535-9786


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