BACKGROUND: We examined the impact of prophylactic IABP insertion in EuroSCORE-stratified high-risk cardiac surgery patients with a score ≥8. MATERIAL AND METHODS: A randomized trial with 104 patients eitherwithout prophylactic IABP insertion (group A, n=52) or with IABP (group B, n=52) was conducted. The primary endpoint was 30-day mortality. RESULTS:The median age of the patients was 74 years and 43% of participants were females. The 30-day mortality did not differ between group A (17.3%) and group B (13.4%; p=0.78). The median hospital stay was 14 days in both groups. Intra- and postoperative IABP support was required by 13 patients (21%) in group A. The median ventilation time (14 hours versus 13 hours), median catecholamine dose, frequency of dialysis-dependent acute renal failure (28% versus 18%), cardiac indices, and frequency of a low cardiac output syndrome (26% versus 25%) did not significantly differ between groups. CONCLUSION:Prophylactic preoperative IABP insertion in EuroSCORE-stratified high-risk patients is not associated with decreased 30-day mortality.
RCT Entities:
BACKGROUND: We examined the impact of prophylactic IABP insertion in EuroSCORE-stratified high-risk cardiac surgery patients with a score ≥8. MATERIAL AND METHODS: A randomized trial with 104 patients either without prophylactic IABP insertion (group A, n=52) or with IABP (group B, n=52) was conducted. The primary endpoint was 30-day mortality. RESULTS: The median age of the patients was 74 years and 43% of participants were females. The 30-day mortality did not differ between group A (17.3%) and group B (13.4%; p=0.78). The median hospital stay was 14 days in both groups. Intra- and postoperative IABP support was required by 13 patients (21%) in group A. The median ventilation time (14 hours versus 13 hours), median catecholamine dose, frequency of dialysis-dependent acute renal failure (28% versus 18%), cardiac indices, and frequency of a low cardiac output syndrome (26% versus 25%) did not significantly differ between groups. CONCLUSION: Prophylactic preoperative IABP insertion in EuroSCORE-stratified high-risk patients is not associated with decreased 30-day mortality.
Authors: Alessandro Parolari; Lorenzo L Pesce; Matteo Trezzi; Laura Cavallotti; Samer Kassem; Claudia Loardi; Davide Pacini; Elena Tremoli; Francesco Alamanni Journal: Ann Thorac Surg Date: 2010-03 Impact factor: 4.330
Authors: Roland Prondzinsky; Henning Lemm; Michael Swyter; Nikolas Wegener; Susanne Unverzagt; Justin M Carter; Martin Russ; Axel Schlitt; Ute Buerke; Arnd Christoph; Hendrik Schmidt; Matthias Winkler; Joachim Thiery; Karl Werdan; Michael Buerke Journal: Crit Care Med Date: 2010-01 Impact factor: 7.598