Literature DB >> 22031079

The impact of leprosy on health-related quality of life.

Anselmo Alves Lustosa1, Lídya Tolstenko Nogueira, José Ivo dos Santos Pedrosa, João Batista Mendes Teles, Viriato Campelo.   

Abstract

INTRODUCTION: Leprosy is a potentially disabling infectious disease that evolves into emotional issues due to the prejudice that persists about the illness. The endemic has declined substantially with multidrug therapy (MDT) in the 80's; however, new demands associated with the reduction of stigma and the improvement of the affected people's quality of life have emerged. In Brazil, leprosy is still a public health problem. Piauí is the second state in the Northeast in prevalence and detection, and Teresina is a hyperendemic city. This study aimed to analyze the health-related quality of life (HRQoL) of people in treatment for leprosy in Teresina/PI.
METHODS: An observational study was conducted using the SF-36 (a specific questionnaire for assessing quality of life), which sought the determinants of poor quality of life among people with leprosy, outlining the sociodemographic, clinical, and epidemiological characteristics of the 107 patients interviewed.
RESULTS: The correlations between the variables showed five determinants of HRQoL: late diagnosis, multibacillary forms, reactions, disability diagnosis grade II, and prejudice. The profile of the participants showed that leprosy still affects the lower social classes in historically endemic areas, causing high percentages of secondary injuries that compromise the work capacity and quality of life of the affected people, perpetuating the stigma associated with the disease.
CONCLUSIONS: The study reinforces the need to implement more effective strategies of disease control, due to the development of severe and disabling forms of leprosy is directly related to poor HRQoL in the same cured patient.

Entities:  

Mesh:

Year:  2011        PMID: 22031079     DOI: 10.1590/s0037-86822011000500019

Source DB:  PubMed          Journal:  Rev Soc Bras Med Trop        ISSN: 0037-8682            Impact factor:   1.581


  21 in total

1.  Transcriptional changes that characterize the immune reactions of leprosy.

Authors:  Kathryn M Dupnik; Thomas B Bair; Andressa O Maia; Francianne M Amorim; Marcos R Costa; Tatjana S L Keesen; Joanna G Valverde; Maria do Carmo A P Queiroz; Lúcio L Medeiros; Nelly L de Lucena; Mary E Wilson; Mauricio L Nobre; Warren D Johnson; Selma M B Jeronimo
Journal:  J Infect Dis       Date:  2014-11-14       Impact factor: 5.226

2.  Leprosy treatment dropout: a systematic review.

Authors:  Régio José Santiago Girão; Nara Lívia Rezende Soares; Juliana Viana Pinheiro; Giuliano da Paz Oliveira; Sionara Melo Figueiredo de Carvalho; Luiz Carlos de Abreu; Vitor E Valenti; Fernando Luiz Affonso Fonseca
Journal:  Int Arch Med       Date:  2013-08-30

3.  Factors affecting perceived stigma in leprosy affected persons in western Nepal.

Authors:  Bipin Adhikari; Nils Kaehler; Robert S Chapman; Shristi Raut; Paul Roche
Journal:  PLoS Negl Trop Dis       Date:  2014-06-05

4.  Cross-cultural adaptation of the EMIC Stigma Scale for people with leprosy in Brazil.

Authors:  Fabiane Frota da Rocha Morgado; Erika Maria Kopp Xavier da Silveira; Anna Maria Sales; Lilian Pinheiro Rodrigues do Nascimento; Euzenir Nunes Sarno; José Augusto da Costa Nery; Aldair J Oliveira; Ximena Illarramendi
Journal:  Rev Saude Publica       Date:  2017-09-04       Impact factor: 2.106

5.  Peripheral nerve abnormality in HIV leprosy patients.

Authors:  Marilia Brasil Xavier; Mariana Garcia Borges do Nascimento; Keila de Nazare Madureira Batista; Danusa Neves Somensi; Fernando Octavio Machado Juca Neto; Thomaz Xavier Carneiro; Claudia Maria Castro Gomes; Carlos Eduardo Pereira Corbett
Journal:  PLoS Negl Trop Dis       Date:  2018-07-18

6.  Leprosy reactions: coinfections as a possible risk factor.

Authors:  Ana Carolina F Motta; Karla Juliana Pereira; Daniela Chaves Tarquínio; Mariana Bellini Vieira; Karina Miyake; Norma Tiraboschi Foss
Journal:  Clinics (Sao Paulo)       Date:  2012-10       Impact factor: 2.365

7.  Health-related quality of life, depression, and self-esteem in adolescents with leprosy-affected parents: results of a cross-sectional study in Nepal.

Authors:  Nobuko Yamaguchi; Krishna C Poudel; Masamine Jimba
Journal:  BMC Public Health       Date:  2013-01-10       Impact factor: 3.295

8.  The impact of podoconiosis on quality of life in Northern Ethiopia.

Authors:  Elizabeth Mousley; Kebede Deribe; Abreham Tamiru; Gail Davey
Journal:  Health Qual Life Outcomes       Date:  2013-07-17       Impact factor: 3.186

9.  Patterns of migration and risks associated with leprosy among migrants in Maranhão, Brazil.

Authors:  Christine Murto; Frédérique Chammartin; Karolin Schwarz; Lea Marcia Melo da Costa; Charles Kaplan; Jorg Heukelbach
Journal:  PLoS Negl Trop Dis       Date:  2013-09-05

10.  Good quality of life in former Buruli ulcer patients with small lesions: long-term follow-up of the BURULICO trial.

Authors:  Sandor Klis; Adelita Ranchor; Richard O Phillips; Kabiru M Abass; Wilson Tuah; Susanne Loth; Kristien Velding; Tjip S van der Werf; Ymkje Stienstra
Journal:  PLoS Negl Trop Dis       Date:  2014-07-10
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