Literature DB >> 22030612

The new date, new format, new goals and new sponsor of the Archon Genomics X PRIZE competition.

Larry Kedes1, Grant Campany.   

Abstract

The Archon Genomics X PRIZE presented by MEDCO is a $10 million prize for whole human genome sequencing that will test 100 samples and establish a defined method for determining quality and cost per genome. The contest will entail a head-to-head competition starting on 3 January 2013. The $10 million grand prize will be awarded to the first team to meet all the quality standards. If there is no grand prize winner, lesser awards will be made for single achievements in the three categories of accuracy, completeness and haplotype phasing. Similar to the open comment period offered earlier this year for the validation protocol, the X PRIZE Foundation seeks commentary from the scientific community on the revised competition format and judging criteria prior to publishing final rules as part of a master agreement with competing teams next year. The official validation protocol will make the competition judging transparent and fair using multiple standard techniques and robust bioinformatics. With sponsorship from Medco Health Solutions (MEDCO), the 100 samples will be derived from genomes of appropriately consented centenarian subjects. At the conclusion of the contest, the data from the redundantly sequenced genomes will be deposited into a scientific database and provide a heretofore unrealized depth of sequence data based on multiple technologies. The sample set and the bioinformatic pipeline will also be made available to the scientific community.

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Year:  2011        PMID: 22030612     DOI: 10.1038/ng.988

Source DB:  PubMed          Journal:  Nat Genet        ISSN: 1061-4036            Impact factor:   38.330


  1 in total

1.  The Archon Genomics X PRIZE for whole human genome sequencing.

Authors:  Larry Kedes; Edison T Liu
Journal:  Nat Genet       Date:  2010-11       Impact factor: 38.330

  1 in total
  5 in total

1.  SMaSH: a benchmarking toolkit for human genome variant calling.

Authors:  Ameet Talwalkar; Jesse Liptrap; Julie Newcomb; Christopher Hartl; Jonathan Terhorst; Kristal Curtis; Ma'ayan Bresler; Yun S Song; Michael I Jordan; David Patterson
Journal:  Bioinformatics       Date:  2014-06-03       Impact factor: 6.937

Review 2.  Sequencing approaches in cancer treatment.

Authors:  D Sekar; K Thirugnanasambantham; V I Hairul Islam; S Saravanan
Journal:  Cell Prolif       Date:  2014-08-07       Impact factor: 6.831

Review 3.  What are we learning from the cancer genome?

Authors:  Eric A Collisson; Raymond J Cho; Joe W Gray
Journal:  Nat Rev Clin Oncol       Date:  2012-09-11       Impact factor: 66.675

4.  Genetic Testing and Type 2 Diabetes Risk Awareness.

Authors:  Mary de Groot; Jennifer Wessel
Journal:  Diabetes Educ       Date:  2014-03-19       Impact factor: 2.140

5.  Sequence verification of synthetic DNA by assembly of sequencing reads.

Authors:  Mandy L Wilson; Yizhi Cai; Regina Hanlon; Samantha Taylor; Bastien Chevreux; João C Setubal; Brett M Tyler; Jean Peccoud
Journal:  Nucleic Acids Res       Date:  2012-10-04       Impact factor: 16.971

  5 in total

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