Literature DB >> 22029354

Beyond the lateral resolution limit by phase imaging.

Yann Cotte1, M Fatih Toy, Christian Depeursinge.   

Abstract

We present a theory to extend the classical Abbe resolution limit by introducing a spatially varying phase into the illumination beam of a phase imaging system. It allows measuring lateral and axial distance differences between point sources to a higher accuracy than intensity imaging alone. Various proposals for experimental realization are debated. Concretely, the phase of point scatterers' interference is experimentally visualized by high numerical aperture (NA = 0.93) digital holographic microscopy combined with angular scanning. Proof-of-principle measurements are presented by using sub-wavelength nanometric holes on an opaque metallic film. In this manner, Rayleighs classical two-point resolution condition can be rebuilt. With different illumination phases, enhanced bandpass information content is demonstrated, and its spatial resolution is theoretically shown to be potentially signal-to-noise ratio limited.

Mesh:

Year:  2011        PMID: 22029354     DOI: 10.1117/1.3640812

Source DB:  PubMed          Journal:  J Biomed Opt        ISSN: 1083-3668            Impact factor:   3.170


  2 in total

Review 1.  Review of quantitative phase-digital holographic microscopy: promising novel imaging technique to resolve neuronal network activity and identify cellular biomarkers of psychiatric disorders.

Authors:  Pierre Marquet; Christian Depeursinge; Pierre J Magistretti
Journal:  Neurophotonics       Date:  2014-09-22       Impact factor: 3.593

2.  Tomographic flow cytometry by digital holography.

Authors:  Francesco Merola; Pasquale Memmolo; Lisa Miccio; Roberto Savoia; Martina Mugnano; Angelo Fontana; Giuliana D'Ippolito; Angela Sardo; Achille Iolascon; Antonella Gambale; Pietro Ferraro
Journal:  Light Sci Appl       Date:  2017-04-07       Impact factor: 17.782

  2 in total

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