Literature DB >> 2201899

Differential repair of UV damage in rad mutants of Saccharomyces cerevisiae: a possible function of G2 arrest upon UV irradiation.

C Terleth1, P Schenk, R Poot, J Brouwer, P van de Putte.   

Abstract

After UV irradiation, the transcriptionally active MAT alpha locus in Saccharomyces cerevisiae is preferentially repaired compared with the inactive HML alpha locus. The effect of rad mutations from three different epistasis groups on differential repair was investigated. Three mutants, rad9, rad16, and rad24, were impaired in the removal of UV dimers from the inactive HML alpha locus, whereas they had generally normal repair of the active MAT alpha locus. Since RAD9 is necessary for G2 arrest after UV irradiation, we propose that the G2 stage plays a role in making the dimers accessible for repair, at least in the repressed HML alpha locus.

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Year:  1990        PMID： 2201899      PMCID： PMC361057          DOI： 10.1128/mcb.10.9.4678-4684.1990

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  27 in total

1.  Differential repair of UV damage in Saccharomyces cerevisiae.

Authors:  C Terleth; C A van Sluis; P van de Putte
Journal:  Nucleic Acids Res       Date:  1989-06-26       Impact factor: 16.971

Review 2.  DNA repair at the level of the gene.

Authors:  V A Bohr; K Wassermann
Journal:  Trends Biochem Sci       Date:  1988-11       Impact factor: 13.807

Review 3.  Life cycle of the budding yeast Saccharomyces cerevisiae.

Authors:  I Herskowitz
Journal:  Microbiol Rev       Date:  1988-12

Review 4.  Transcriptional regulation in the yeast life cycle.

Authors:  K Nasmyth; D Shore
Journal:  Science       Date:  1987-09-04       Impact factor: 47.728

5.  Cloning and sequence analysis of the Saccharomyces cerevisiae RAD9 gene and further evidence that its product is required for cell cycle arrest induced by DNA damage.

Authors:  R H Schiestl; P Reynolds; S Prakash; L Prakash
Journal:  Mol Cell Biol       Date:  1989-05       Impact factor: 4.272

Review 6.  Deoxyribonucleic acid repair in the yeast Saccharomyces cerevisiae.

Authors:  E C Friedberg
Journal:  Microbiol Rev       Date:  1988-03

7.  Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene.

Authors:  I Mellon; G Spivak; P C Hanawalt
Journal:  Cell       Date:  1987-10-23       Impact factor: 41.582

8.  The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae.

Authors:  T A Weinert; L H Hartwell
Journal:  Science       Date:  1988-07-15       Impact factor: 47.728

9.  DNA damage and repair in normal, xeroderma pigmentosum and XP revertant cells analyzed by gel electrophoresis: excision of cyclobutane dimers from the whole genome is not necessary for cell survival.

Authors:  J E Cleaver
Journal:  Carcinogenesis       Date:  1989-09       Impact factor: 4.944

10.  Preferential DNA repair in expressed genes.

Authors:  P C Hanawalt
Journal:  Environ Health Perspect       Date:  1987-12       Impact factor: 9.031
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  25 in total

1.  Photoreactivation of UV-induced cyclobutane pyrimidine dimers in the MFA2 gene of Saccharomyces cerevisiae.

Authors:  Nerys R Morse; Valerie Meniel; Raymond Waters
Journal:  Nucleic Acids Res       Date:  2002-04-15       Impact factor: 16.971

2.  Xeroderma pigmentosum complementation group C cells remove pyrimidine dimers selectively from the transcribed strand of active genes.

Authors:  J Venema; A van Hoffen; V Karcagi; A T Natarajan; A A van Zeeland; L H Mullenders
Journal:  Mol Cell Biol       Date:  1991-08       Impact factor: 4.272

3.  The Sir1 protein's association with a silenced chromosome domain.

Authors:  K A Gardner; C A Fox
Journal:  Genes Dev       Date:  2001-01-15       Impact factor: 11.361

Review 4.  DNA repair mechanisms and the bypass of DNA damage in Saccharomyces cerevisiae.

Authors:  Serge Boiteux; Sue Jinks-Robertson
Journal:  Genetics       Date:  2013-04       Impact factor: 4.562

Review 5.  Nucleotide excision repair in yeast.

Authors:  K S Sweder
Journal:  Curr Genet       Date:  1994-12       Impact factor: 3.886

6.  A UV-responsive G2 checkpoint in rodent cells.

Authors:  D K Orren; L N Petersen; V A Bohr
Journal:  Mol Cell Biol       Date:  1995-07       Impact factor: 4.272

7.  Regulation of the Saccharomyces cerevisiae DNA repair gene RAD16.

Authors:  D D Bang; V Timmermans; R Verhage; A M Zeeman; P van de Putte; J Brouwer
Journal:  Nucleic Acids Res       Date:  1995-05-25       Impact factor: 16.971

8.  Interaction of excision repair gene products and mitotic recombination functions in yeast.

Authors:  B A Montelone; B C Liang-Chong
Journal:  Curr Genet       Date:  1993-12       Impact factor: 3.886

9.  RAD9-dependent G1 arrest defines a second checkpoint for damaged DNA in the cell cycle of Saccharomyces cerevisiae.

Authors:  W Siede; A S Friedberg; E C Friedberg
Journal:  Proc Natl Acad Sci U S A       Date:  1993-09-01       Impact factor: 11.205

10.  The NEF4 complex regulates Rad4 levels and utilizes Snf2/Swi2-related ATPase activity for nucleotide excision repair.

Authors:  Kerrington L Ramsey; Joshua J Smith; Arindam Dasgupta; Nazif Maqani; Patrick Grant; David T Auble
Journal:  Mol Cell Biol       Date:  2004-07       Impact factor: 4.272
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