| Literature DB >> 22016112 |
Liu Yang1, Xiaobing Zhang, Mao Ye, Jianhui Jiang, Ronghua Yang, Ting Fu, Yan Chen, Kemin Wang, Chen Liu, Weihong Tan.
Abstract
The combination of aptamers with novel nanomaterials, including nanomaterial-based aptamer bioconjugates has attracted considerable interest and has led to a wide variety of applications. In this review, we discuss how a variety of nanomaterials, including gold, silica and magnetic nanoparticles, as well as carbon nanotubes, hydrogels, liposomes and micelles, have been used to functionalize aptamers for a variety of applications. These aptamer functionalized materials have led to advances in amplified biosensing, cancer cell-specific recognition, high-efficiency separation, and targeted drug delivery.Entities:
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Year: 2011 PMID： 22016112 PMCID： PMC3245877 DOI： 10.1016/j.addr.2011.10.002
Source DB: PubMed Journal: Adv Drug Deliv Rev ISSN： 0169-409X Impact factor: 15.470