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Literature DB >> 15382892

Aptamer-functionalized Au nanoparticles for the amplified optical detection of thrombin.

Valeri Pavlov¹, Yi Xiao, Bella Shlyahovsky, Itamar Willner.

Abstract

The catalytic enlargement of aptamer-functionalized Au nanoparticles amplifies the optical detection of aptamer-thrombin complexes in solution and on surfaces.

Entities: Chemical Gene

Mesh：

Substances：

Year: 2004 PMID： 15382892 DOI： 10.1021/ja046970u

Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419

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Cited

72 in total

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Aptamer-functionalized Au nanoparticles for the amplified optical detection of thrombin.

Review 1. Gold nanoparticles in chemical and biological sensing.

Review 2. Molecular diagnostic and drug delivery agents based on aptamer-nanomaterial conjugates.

3. A gold nanoparticle based approach for screening triplex DNA binders.

4. Protein detection via direct enzymatic amplification of short DNA aptamers.

5. Gold nanoparticles-based protease assay.

Review 6. Functional nucleic acid sensors.

7. Multivalent DNA nanospheres for enhanced capture of cancer cells in microfluidic devices.

8. Molecular recognition by gold, silver and copper nanoparticles.

Review 9. Silver nanoparticle-oligonucleotide conjugates based on DNA with triple cyclic disulfide moieties.

10. Isolating single stranded DNA using a microfluidic dialysis device.