Literature DB >> 22014098

Transfusion safety in francophone African countries: an analysis of strategies for the medical selection of blood donors.

Claude Tayou Tagny1, Maxime Diané Kouao, Hamane Touré, Jalel Gargouri, Ahamada Said Fazul, Siaka Ouattara, Ludovic Anani, Habiba Othmani, Lochina Feteke, Honorine Dahourou, Guy Olivier Mbensa, Simplice Molé, Yacouba Nébié, Madeleine Mbangue, Michel Toukam, Mahommed Ould Boulahi, Lalatiana Valisoa Andriambelo, Olivat Rakoto, Mounirou Baby, Rakia Yahaya, Amelia Bokilo, Florent Senyana, Dora Mbanya, Caroline Shiboski, Edward L Murphy, Jean Jacques Lefrère.   

Abstract

BACKGROUND: The goal of selecting a healthy blood donor is to safeguard donors and reduce the risks of infections and immunologic complications for recipients. STUDY DESIGN AND METHODS: To evaluate the blood donor selection process, a survey was conducted in 28 blood transfusion centers located in 15 francophone African countries. Data collected included availability of blood products, risk factors for infection identified among blood donor candidates, the processing of the information collected before blood collection, the review process for the medical history of blood donor candidates, and deferral criteria for donor candidates.
RESULTS: During the year 2009, participating transfusion centers identified 366,924 blood donor candidates. A mean of 13% (range, 0%-36%) of the donor candidates were excluded based solely on their medical status. The main risk factors for blood-borne infections were having multiple sex partners, sexual intercourse with occasional partners, and religious scarification. Most transfusion centers collected this information verbally instead of having a written questionnaire. The topics least addressed were the possible complications relating to the donation, religious scarifications, and history of sickle cell anemia and hemorrhage. Only three centers recorded the temperature of the blood donors. The deferral criteria least reported were sickle cell anemia, piercing, scarification, and tattoo.
CONCLUSIONS: The medical selection process was not performed systemically and thoroughly enough, given the regional epidemiologic risks. It is essential to identify the risk factors specific to francophone African countries and modify the current medical history questionnaires to develop a more effective and relevant selection process.
© 2011 American Association of Blood Banks.

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Year:  2011        PMID: 22014098      PMCID: PMC3668689          DOI: 10.1111/j.1537-2995.2011.03391.x

Source DB:  PubMed          Journal:  Transfusion        ISSN: 0041-1132            Impact factor:   3.157


  33 in total

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1.  Reducing risks of Transfusion-transmitted infections in a resource-limited hospital-based blood bank: the case of the Yaoundé University Teaching Hospital, Cameroon.

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5.  Seroprevalence of transfusion-transmissible infections among blood donors at National Blood Transfusion Service, Eritrea: a seven-year retrospective study.

Authors:  Nejat Siraj; Oliver Okoth Achila; John Issac; Efrem Menghisteab; Maedn Hailemariam; Semere Hagos; Yosan Gebremeskel; Daniel Tesfamichael
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6.  Blood Safety Status in WHO African Region Countries: Lessons Learnt from Mauritius.

Authors:  André Loua; Janaki Sonoo; Laurent Musango; Jean Baptiste Nikiema; Thomas Lapnet-Moustapha
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7.  Seroprevalence of transfusion transmitted infections among blood donors in Gash Barka Zonal Blood Transfusion Center, Barentu, Eritrea, 2014 through 2017.

Authors:  Bereket Habteslasie Gebrecherkos; Danait Tareke Tesfaldet; Kibrom Solomon Teklu; Mesuda Abrhum Mohammed; Selihom Tesfaslase Ghedel; Yacob Tesfamichael Keleta; Oliver Okoth Achila; Absera Woldu Haile
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8.  Trends in serological markers of transfusion transmissible infections in blood donations at the Bamenda Hospital-based Blood Service, Cameroon.

Authors:  Moses Samje; Victor N Fondoh; Georges Nguefack-Tsague; Laure K J Kamalieuk; Dora Mbanya; Edward L Murphy; Claude T Tagny
Journal:  Transfus Clin Biol       Date:  2021-06-05       Impact factor: 1.406

9.  Impact of Multiplex PCR in Reducing the Risk of Residual Transfusion-Transmitted Human Immunodeficiency and Hepatitis B and C Viruses in Burkina Faso.

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10.  Proficiency Testing of Viral Marker Screening in African Blood Centers - Seven African Countries, 2017.

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Journal:  MMWR Morb Mortal Wkly Rep       Date:  2019-10-25       Impact factor: 17.586

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