Literature DB >> 22009282

Stroke: disappointing results for clazosentan in CONSCIOUS-2.

Philip M Meyers, E Sander Connolly.   

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Year:  2011        PMID： 22009282     DOI： 10.1038/nrneurol.2011.168

Source DB:  PubMed          Journal:  Nat Rev Neurol        ISSN： 1759-4758            Impact factor:   42.937


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  9 in total

1.  Clazosentan, an endothelin receptor antagonist, in patients with aneurysmal subarachnoid haemorrhage undergoing surgical clipping: a randomised, double-blind, placebo-controlled phase 3 trial (CONSCIOUS-2).

Authors:  R Loch Macdonald; Randall T Higashida; Emanuela Keller; Stephan A Mayer; Andy Molyneux; Andreas Raabe; Peter Vajkoczy; Isabel Wanke; Doris Bach; Aline Frey; Angelina Marr; Sébastien Roux; Neal Kassell
Journal:  Lancet Neurol       Date:  2011-06-02       Impact factor: 44.182

2.  Angiographic vasospasm is strongly correlated with cerebral infarction after subarachnoid hemorrhage.

Authors:  R Webster Crowley; R Medel; Aaron S Dumont; Don Ilodigwe; Neal F Kassell; Stephan A Mayer; Daniel Ruefenacht; Peter Schmiedek; Stephan Weidauer; Alberto Pasqualin; R Loch Macdonald
Journal:  Stroke       Date:  2011-02-24       Impact factor: 7.914

Review 3.  Time trends in outcome of subarachnoid hemorrhage: Population-based study and systematic review.

Authors:  C E Lovelock; G J E Rinkel; P M Rothwell
Journal:  Neurology       Date:  2010-04-07       Impact factor: 9.910

Review 4.  Spreading depolarization: a possible new culprit in the delayed cerebral ischemia of subarachnoid hemorrhage.

Authors:  Lewis Z Leng; Matthew E Fink; Costantino Iadecola
Journal:  Arch Neurol       Date:  2010-09-13

Review 5.  Endothelin related pathophysiology in cerebral vasospasm: what happens to the cerebral vessels?

Authors:  Hartmut Vatter; Jürgen Konczalla; Volker Seifert
Journal:  Acta Neurochir Suppl       Date:  2011

6.  Dissociation of vasospasm and secondary effects of experimental subarachnoid hemorrhage by clazosentan.

Authors:  Mohammed Sabri; Jinglu Ai; R Loch Macdonald
Journal:  Stroke       Date:  2011-03-31       Impact factor: 7.914

7.  Quantitative analysis of hemorrhage volume for predicting delayed cerebral ischemia after subarachnoid hemorrhage.

Authors:  Sang-Bae Ko; H Alex Choi; Amanda Mary Carpenter; Raimund Helbok; J Michael Schmidt; Neeraj Badjatia; Jan Claassen; E Sander Connolly; Stephan A Mayer; Kiwon Lee
Journal:  Stroke       Date:  2011-01-21       Impact factor: 7.914

8.  Clazosentan: an endothelin receptor antagonist for treatment of vasospasm after subarachnoid hemorrhage.

Authors:  R Loch Macdonald
Journal:  Expert Opin Investig Drugs       Date:  2008-11       Impact factor: 6.206

Review 9.  Microthrombosis after aneurysmal subarachnoid hemorrhage: an additional explanation for delayed cerebral ischemia.

Authors:  Mervyn D I Vergouwen; Marinus Vermeulen; Bert A Coert; Erik S G Stroes; Yvo B W E M Roos
Journal:  J Cereb Blood Flow Metab       Date:  2008-07-16       Impact factor: 6.200
  9 in total
  8 in total

Review 1.  Delayed Cerebral Ischemia after Subarachnoid Hemorrhage: Beyond Vasospasm and Towards a Multifactorial Pathophysiology.

Authors:  Joseph R Geraghty; Fernando D Testai
Journal:  Curr Atheroscler Rep       Date:  2017-10-23       Impact factor: 5.113

Review 2.  Biomarkers as outcome predictors in subarachnoid hemorrhage--a systematic review.

Authors:  Caron M Hong; Cigdem Tosun; David B Kurland; Volodymyr Gerzanich; David Schreibman; J Marc Simard
Journal:  Biomarkers       Date:  2014-02-05       Impact factor: 2.658

3.  Severe cognitive impairment in aneurysmal subarachnoid hemorrhage: Predictors and relationship to functional outcome.

Authors:  Joseph R Geraghty; Melissa N Lara-Angulo; Milen Spegar; Jenna Reeh; Fernando D Testai
Journal:  J Stroke Cerebrovasc Dis       Date:  2020-06-20       Impact factor: 2.136

Review 4.  [Aneurysmal subarachnoid hemorrhage].

Authors:  P Kellner; D Stoevesandt; J Soukup; M Bucher; C Raspé
Journal:  Anaesthesist       Date:  2012-09       Impact factor: 1.041

Review 5.  Neuroinflammation and Microvascular Dysfunction After Experimental Subarachnoid Hemorrhage: Emerging Components of Early Brain Injury Related to Outcome.

Authors:  Joseph R Geraghty; Joseph L Davis; Fernando D Testai
Journal:  Neurocrit Care       Date:  2019-10       Impact factor: 3.210

6.  Interleukin-6 as a Prognostic Biomarker in Ruptured Intracranial Aneurysms.

Authors:  Hung-Wen Kao; Kwo-Whei Lee; Chen-Ling Kuo; Ching-Shan Huang; Wan-Min Tseng; Chin-San Liu; Ching-Po Lin
Journal:  PLoS One       Date:  2015-07-15       Impact factor: 3.240

Review 7.  Inflammation, cerebral vasospasm, and evolving theories of delayed cerebral ischemia.

Authors:  Kevin R Carr; Scott L Zuckerman; J Mocco
Journal:  Neurol Res Int       Date:  2013-08-22

8.  Blood-filled cerebrospinal fluid-enhanced pericyte microvasculature contraction in rat retina: A novel in vitro study of subarachnoid hemorrhage.

Authors:  Zhi Liu; Qiang Li; Gaoyu Cui; Gang Zhu; Weihua Tang; Hengli Zhao; John H Zhang; Yujie Chen; Hua Feng
Journal:  Exp Ther Med       Date:  2016-09-01       Impact factor: 2.447
  8 in total

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