Literature DB >> 22009076

Has the new TNM classification for colorectal cancer improved care?

Iris D Nagtegaal1, Phil Quirke, Hans-Joachim Schmoll.   

Abstract

In 2009, the Union for International Cancer Control issued the seventh edition of the well-used T (tumor), N (node), and M (metastasis) classification guidelines. There has been a continual refinement of the staging for colorectal cancer since this system for assessing tumor stage was initially adopted and it has been used to guide treatment decisions for over 50 years. However, the outcome after therapy for patients with colorectal cancer is very variable, even when patients are assigned to the same TNM category. This article assesses the changes that have been made since the sixth edition and discusses whether they are, in fact, informative improvements for a practicing clinician.

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Year:  2011        PMID: 22009076     DOI: 10.1038/nrclinonc.2011.157

Source DB:  PubMed          Journal:  Nat Rev Clin Oncol        ISSN: 1759-4774            Impact factor:   66.675


  29 in total

1.  'Evidence-based medicine: the time has come to set standards for staging'. Is a radical overhaul really needed?

Authors:  Leslie H Sobin; Carolyn A Compton; Mary Gospodarowicz; Frederick L Greene; Leonard L Gunderson; J Milburn Jessup; Christian Wittekind
Journal:  J Pathol       Date:  2010-08       Impact factor: 7.996

2.  Marked improvements in survival of patients with rectal cancer in the Netherlands following changes in therapy, 1989-2006.

Authors:  M A G Elferink; L N van Steenbergen; P Krijnen; V E P P Lemmens; H J Rutten; C A M Marijnen; I D Nagtegaal; H E Karim-Kos; E de Vries; S Siesling
Journal:  Eur J Cancer       Date:  2010-02-19       Impact factor: 9.162

3.  Longer time interval between completion of neoadjuvant chemoradiation and surgical resection does not improve downstaging of rectal carcinoma.

Authors:  David E Stein; Najjia N Mahmoud; Pramila Rani Anné; Deborah G Rose; Gerald A Isenberg; Scott D Goldstein; Edith Mitchell; Robert D Fry
Journal:  Dis Colon Rectum       Date:  2003-04       Impact factor: 4.585

Review 4.  Neoadjuvant therapy in rectal cancer.

Authors:  Fergal J Fleming; Lars Påhlman; John R T Monson
Journal:  Dis Colon Rectum       Date:  2011-07       Impact factor: 4.585

5.  The new tumor, node, and metastasis staging system.

Authors:  Ramón Rami-Porta; Vanessa Bolejack; Peter Goldstraw
Journal:  Semin Respir Crit Care Med       Date:  2011-04-15       Impact factor: 3.119

6.  No downstaging after short-term preoperative radiotherapy in rectal cancer patients.

Authors:  C A Marijnen; I D Nagtegaal; E Klein Kranenbarg; J Hermans; C J van de Velde; J W Leer; J H van Krieken
Journal:  J Clin Oncol       Date:  2001-04-01       Impact factor: 44.544

7.  Preoperative radiochemotherapy is successful also in patients with locally advanced rectal cancer who have intrinsically high apoptotic tumours.

Authors:  M J E M Gosens; R C Dresen; H J T Rutten; G A P Nieuwenhuijzen; J A W M van der Laak; H Martijn; I Tan-Go; I D Nagtegaal; A J C van den Brule; J H J M van Krieken
Journal:  Ann Oncol       Date:  2008-07-29       Impact factor: 32.976

8.  Revised TN categorization for colon cancer based on national survival outcomes data.

Authors:  Leonard L Gunderson; John Milburn Jessup; Daniel J Sargent; Frederick L Greene; Andrew K Stewart
Journal:  J Clin Oncol       Date:  2009-11-30       Impact factor: 44.544

9.  The IASLC Lung Cancer Staging Project: proposals regarding the relevance of TNM in the pathologic staging of small cell lung cancer in the forthcoming (seventh) edition of the TNM classification for lung cancer.

Authors:  Eric Vallières; Frances A Shepherd; John Crowley; Paul Van Houtte; Pieter E Postmus; Desmond Carney; Kari Chansky; Zeba Shaikh; Peter Goldstraw
Journal:  J Thorac Oncol       Date:  2009-09       Impact factor: 15.609

10.  TNM, sixth edition: new developments in general concepts and rules.

Authors:  Leslie H Sobin
Journal:  Semin Surg Oncol       Date:  2003
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  62 in total

Review 1.  The role of microRNAs in colorectal cancer.

Authors:  Aaron J Schetter; Hirokazu Okayama; Curtis C Harris
Journal:  Cancer J       Date:  2012 May-Jun       Impact factor: 3.360

2.  miR-15a-5p, A Novel Prognostic Biomarker, Predicting Recurrent Colorectal Adenocarcinoma.

Authors:  Christos K Kontos; Panagiotis Tsiakanikas; Margaritis Avgeris; Iordanis N Papadopoulos; Andreas Scorilas
Journal:  Mol Diagn Ther       Date:  2017-08       Impact factor: 4.074

Review 3.  EURECCA consensus conference highlights about colorectal cancer clinical management: the pathologists expert review.

Authors:  P Quirke; N P West; I D Nagtegaal
Journal:  Virchows Arch       Date:  2014-01-24       Impact factor: 4.064

4.  Additional Support for the Introduction of Immune Cell Quantification in Colorectal Cancer Classification.

Authors:  Robert L Ferris; Jérôme Galon
Journal:  J Natl Cancer Inst       Date:  2016-05-12       Impact factor: 13.506

Review 5.  The significance of tumor-associated immune response in molecular taxonomy, prognosis and therapy of colorectal cancer patients.

Authors:  Andreas Nearchou; George Pentheroudakis
Journal:  Ann Transl Med       Date:  2016-07

Review 6.  [Pathology of the R1 classification in visceral cancer surgery].

Authors:  M J Pollheimer; C Langner
Journal:  Chirurg       Date:  2017-09       Impact factor: 0.955

7.  Intratumoral CD3 and CD8 T-cell Densities Associated with Relapse-Free Survival in HCC.

Authors:  Andrew Gabrielson; Yunan Wu; Hongkun Wang; Jiji Jiang; Bhaskar Kallakury; Zoran Gatalica; Sandeep Reddy; David Kleiner; Thomas Fishbein; Lynt Johnson; Eddie Island; Rohit Satoskar; Filip Banovac; Reena Jha; Jaydeep Kachhela; Perry Feng; Tiger Zhang; Anteneh Tesfaye; Petra Prins; Christopher Loffredo; John Marshall; Louis Weiner; Michael Atkins; Aiwu Ruth He
Journal:  Cancer Immunol Res       Date:  2016-03-11       Impact factor: 11.151

8.  CD169 identifies an activated CD8(+) T cell subset in regional lymph nodes that predicts favorable prognosis in colorectal cancer patients.

Authors:  Jiali Zhang; Jing Xu; Rong-Xin Zhang; Yi Zhang; Qing-Jian Ou; Jin-Qing Li; Ze-Zhou Jiang; Xiao-Jun Wu; Yu-Jing Fang; Limin Zheng
Journal:  Oncoimmunology       Date:  2016-04-29       Impact factor: 8.110

Review 9.  The immune contexture and Immunoscore in cancer prognosis and therapeutic efficacy.

Authors:  Daniela Bruni; Helen K Angell; Jérôme Galon
Journal:  Nat Rev Cancer       Date:  2020-08-04       Impact factor: 60.716

Review 10.  Assessment of lymph node involvement in colorectal cancer.

Authors:  Mark L H Ong; John B Schofield
Journal:  World J Gastrointest Surg       Date:  2016-03-27
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