BACKGROUND: Cervical total disc replacement (CTDR) is an alternative to anterior fusion. Therefore, it is desirable to have an accurate in vivo measurement of prosthetic kinematics and assessment of implant stability relative to the adjacent vertebrae. PURPOSE: To devise an in vivo CT-based method to analyze the kinematics of cervical total disc replacements (CTDR), specifically of two prosthetic components between two CT scans obtained under different conditions. MATERIAL AND METHODS: Nine patients with CTDR were scanned in flexion and extension of the cervical spine using a clinical CT scanner with a routine low-dose protocol. The flexion and extension CT volume data were spatially registered, and the prosthetic kinematics of two prosthetic components, an upper and a lower, was calculated and expressed in Euler angles and orthogonal linear translations relative to the upper component. For accuracy analysis, a cervical spine model incorporating the same disc replacement as used in the patients was also scanned and processed in the same manner. RESULTS: Analysis of both the model and patients showed good repeatability, i.e. within 2 standard deviations of the mean using the 95% limits of agreement with no overlapping confidence intervals. The accuracy analysis showed that the median error was close to zero. CONCLUSION: The mobility of the cervical spine after total disc replacement can be effectively measured in vivo using CT. This method requires an appropriate patient positioning and scan parameters to achieve suitable image quality.
BACKGROUND: Cervical total disc replacement (CTDR) is an alternative to anterior fusion. Therefore, it is desirable to have an accurate in vivo measurement of prosthetic kinematics and assessment of implant stability relative to the adjacent vertebrae. PURPOSE: To devise an in vivo CT-based method to analyze the kinematics of cervical total disc replacements (CTDR), specifically of two prosthetic components between two CT scans obtained under different conditions. MATERIAL AND METHODS: Nine patients with CTDR were scanned in flexion and extension of the cervical spine using a clinical CT scanner with a routine low-dose protocol. The flexion and extension CT volume data were spatially registered, and the prosthetic kinematics of two prosthetic components, an upper and a lower, was calculated and expressed in Euler angles and orthogonal linear translations relative to the upper component. For accuracy analysis, a cervical spine model incorporating the same disc replacement as used in the patients was also scanned and processed in the same manner. RESULTS: Analysis of both the model and patients showed good repeatability, i.e. within 2 standard deviations of the mean using the 95% limits of agreement with no overlapping confidence intervals. The accuracy analysis showed that the median error was close to zero. CONCLUSION: The mobility of the cervical spine after total disc replacement can be effectively measured in vivo using CT. This method requires an appropriate patient positioning and scan parameters to achieve suitable image quality.
Authors: Cyrus Brodén; Henrik Olivecrona; Gerald Q Maguire; Marilyn E Noz; Michael P Zeleznik; Olof Sköldenberg Journal: Biomed Res Int Date: 2016-07-10 Impact factor: 3.411
Authors: Henrik Olivecrona; Gerald Q Maguire; Marilyn E Noz; Michael P Zeleznik; Uldis Kesteris; Lars Weidenhielm Journal: J Orthop Surg Res Date: 2016-02-24 Impact factor: 2.359
Authors: Volker Otten; Gerald Q Maguire; Marilyn E Noz; Michael P Zeleznik; Kjell G Nilsson; Henrik Olivecrona Journal: Biomed Res Int Date: 2017-01-24 Impact factor: 3.411
Authors: Per Svedmark; Svante Berg; Marilyn E Noz; Gerald Q Maguire; Michael P Zeleznik; Lars Weidenhielm; Gunnar Nemeth; Henrik Olivecrona Journal: Biomed Res Int Date: 2015-10-26 Impact factor: 3.411