Literature DB >> 22006498

Molecular biology of adenoid cystic carcinoma.

Jia Liu1, Chunbo Shao, Marietta L Tan, David Mu, Robert L Ferris, Patrick K Ha.   

Abstract

BACKGROUND: Adenoid cystic carcinoma (ACC) is an unusual salivary gland malignancy that remains poorly understood. Standard treatment, including surgery with postoperative radiation therapy, has attained reasonable local control rates, but the propensity for distant metastases has limited any improvement in survival over time. Our understanding of the molecular mechanisms driving ACC is quite rudimentary, due to the infrequent nature of its occurrence.
METHODS: An extensive literature review was performed on salivary gland ACCs and basic science research findings.
RESULTS: This review highlights many findings that are emerging about the carcinogenesis of ACC including cytogenetics, tumor suppressor genes, oncogenes, epigenetic alterations, mitochondrial alterations, and biomarker studies.
CONCLUSION: Although there have been many discoveries, much still remains unknown about this rare malignancy. © 2011 Wiley Periodicals, Inc. Head Neck, 2011.
Copyright © 2011 Wiley Periodicals, Inc.

Entities:  

Mesh：

Year:  2011        PMID： 22006498      PMCID： PMC3262103          DOI： 10.1002/hed.21849

Source DB:  PubMed          Journal:  Head Neck        ISSN： 1043-3074            Impact factor:   3.147


  134 in total

1.  Imatinib mesylate in patients with adenoid cystic cancers of the salivary glands expressing c-kit: a Princess Margaret Hospital phase II consortium study.

Authors:  Sébastien J Hotte; Eric W Winquist; Elizabeth Lamont; Mary MacKenzie; Everett Vokes; Eric X Chen; Shirley Brown; Gregory R Pond; Anthony Murgo; Lillian L Siu
Journal:  J Clin Oncol       Date:  2005-01-20       Impact factor: 44.544

2.  Promoter methylation of p16INK4a, RASSF1A, and DAPK is frequent in salivary adenoid cystic carcinoma.

Authors:  Jiang Li; Adel El-Naggar; Li Mao
Journal:  Cancer       Date:  2005-08-15       Impact factor: 6.860

3.  Implication of galectin-3 in Wnt signaling.

Authors:  Tatsuo Shimura; Yukinori Takenaka; Tomoharu Fukumori; Soichi Tsutsumi; Kohji Okada; Victor Hogan; Akira Kikuchi; Hiroyuki Kuwano; Avraham Raz
Journal:  Cancer Res       Date:  2005-05-01       Impact factor: 12.701

4.  Copy number gains on 22q13 in adenoid cystic carcinoma of the salivary gland revealed by comparative genomic hybridization and tissue microarray analysis.

Authors:  Kolja Freier; Christa Flechtenmacher; Axel Walch; Sibylle Ohl; Frauke Devens; Bert Burke; Stefan Hassfeld; Peter Lichter; Stefan Joos; Christof Hofele
Journal:  Cancer Genet Cytogenet       Date:  2005-05

5.  Expression of c-kit gene products in known cellular targets of W mutations in normal and W mutant mice--evidence for an impaired c-kit kinase in mutant mice.

Authors:  K Nocka; S Majumder; B Chabot; P Ray; M Cervone; A Bernstein; P Besmer
Journal:  Genes Dev       Date:  1989-06       Impact factor: 11.361

6.  6q- and loss of the Y chromosome--two common deviations in malignant human salivary gland tumors.

Authors:  G Stenman; J Sandros; R Dahlenfors; M Juberg-Ode; J Mark
Journal:  Cancer Genet Cytogenet       Date:  1986-08

7.  The significance of perineural spread in adenoid cystic carcinoma of the major and minor salivary glands.

Authors:  L J Vrielinck; F Ostyn; B van Damme; W van den Bogaert; E Fossion
Journal:  Int J Oral Maxillofac Surg       Date:  1988-06       Impact factor: 2.789

8.  Expression of beta-catenin, E-cadherin and cyclin D1 in adenoid cystic carcinoma of the salivary gland.

Authors:  T Daa; N Kaku; K Kashima; I Nakayama; S Yokoyama
Journal:  J Exp Clin Cancer Res       Date:  2005-03

9.  Beta-6 Integrin, tenascin-C, and MMP-1 expression in salivary gland neoplasms.

Authors:  Trent H Westernoff; Richard C K Jordan; Joseph A Regezi; Daniel M Ramos; Brian L Schmidt
Journal:  Oral Oncol       Date:  2005-02       Impact factor: 5.337

10.  Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion.

Authors:  J Behrens; M M Mareel; F M Van Roy; W Birchmeier
Journal:  J Cell Biol       Date:  1989-06       Impact factor: 10.539
View more
  28 in total

Review 1.  Genetic alterations in salivary gland cancers.

Authors:  Linda X Yin; Patrick K Ha
Journal:  Cancer       Date:  2016-02-29       Impact factor: 6.860

2.  Notch2 signaling contributes to cell growth, invasion, and migration in salivary adenoid cystic carcinoma.

Authors:  Jing Qu; Min Song; Jian Xie; Xiao-Yu Huang; Xiao-Meng Hu; Rui-Huan Gan; Yong Zhao; Li-Song Lin; Jiang Chen; Xu Lin; Da-Li Zheng; You-Guang Lu
Journal:  Mol Cell Biochem       Date:  2015-10-01       Impact factor: 3.396

3.  MYB rearrangement and clinicopathologic characteristics in head and neck adenoid cystic carcinoma.

Authors:  Eleni M Rettig; Marietta Tan; Shizhang Ling; Raluca Yonescu; Justin A Bishop; Carole Fakhry; Patrick K Ha
Journal:  Laryngoscope       Date:  2015-05-11       Impact factor: 3.325

4.  Immunoexpression of GLUT-1 and angiogenic index in pleomorphic adenomas, adenoid cystic carcinomas, and mucoepidermoid carcinomas of the salivary glands.

Authors:  Lélia Batista de Souza; Lucileide Castro de Oliveira; Cassiano Francisco Weege Nonaka; Maria Luiza Diniz de Sousa Lopes; Leão Pereira Pinto; Lélia Maria Guedes Queiroz
Journal:  Eur Arch Otorhinolaryngol       Date:  2017-03-16       Impact factor: 2.503

5.  Whole-Genome Sequencing of Salivary Gland Adenoid Cystic Carcinoma.

Authors:  Eleni M Rettig; C Conover Talbot; Mark Sausen; Sian Jones; Justin A Bishop; Laura D Wood; Collin Tokheim; Noushin Niknafs; Rachel Karchin; Elana J Fertig; Sarah J Wheelan; Luigi Marchionni; Michael Considine; Shizhang Ling; Carole Fakhry; Nickolas Papadopoulos; Kenneth W Kinzler; Bert Vogelstein; Patrick K Ha; Nishant Agrawal
Journal:  Cancer Prev Res (Phila)       Date:  2016-02-09

6.  Prognostic significance of PDCD4 expression in human salivary adenoid cystic carcinoma.

Authors:  Cheng Qi; Yi Shao; Ning Li; Chunyan Zhang; Miaoqing Zhao; Fei Gao
Journal:  Med Oncol       Date:  2013-02-07       Impact factor: 3.064

7.  Expression of PIM-1 in salivary gland adenoid cystic carcinoma: Association with tumor progression and patients' prognosis.

Authors:  Xin Zhu; Yunfang Yu; Xiuxiu Hou; Jiajie Xu; Zhuo Tan; Xilin Nie; Zhiqiang Ling; Minghua Ge
Journal:  Oncol Lett       Date:  2017-11-14       Impact factor: 2.967

8.  miR-21 regulates tumor progression through the miR-21-PDCD4-Stat3 pathway in human salivary adenoid cystic carcinoma.

Authors:  Lie-Hao Jiang; Ming-Hua Ge; Xiu-Xiu Hou; Jun Cao; Si-Si Hu; Xiao-Xiao Lu; Jing Han; Yi-Chen Wu; Xiang Liu; Xin Zhu; Lian-Lian Hong; Pei Li; Zhi-Qiang Ling
Journal:  Lab Invest       Date:  2015-09-14       Impact factor: 5.662

9.  Aquaporin-1 promoter hypermethylation is associated with improved prognosis in salivary gland adenoid cystic carcinoma.

Authors:  Marietta Tan; Chunbo Shao; Justin A Bishop; Zhaoyong Feng; Bruce J Trock; William H Westra; Patrick K Ha
Journal:  Otolaryngol Head Neck Surg       Date:  2014-02-03       Impact factor: 3.497

10.  Expression of ERBB3 binding protein 1 (EBP1) in salivary adenoid cystic carcinoma and its clinicopathological relevance.

Authors:  Jian Sun; Yixi Luo; Zhen Tian; Liang Gu; Shu Chi Xia; Youcheng Yu
Journal:  BMC Cancer       Date:  2012-10-30       Impact factor: 4.430
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.