BACKGROUND: Invasive mucormycosis or aspergillosis is a life-threatening infection. The disease typically occurs in immunocompromised patients (e.g., those with diabetes mellitus or burns) but is rarely serious in otherwise-healthy young trauma patients. METHODS: Case report and literature review. RESULTS: A previously-healthy 22-year-old United States Marine who sustained large soft tissue injuries in support of Operation Enduring Freedom underwent multiple operations in theater to stabilize his wounds. He was evacuated first to Landstuhl Regional Medical Center in Germany and thence to the National Naval Medical Center in Maryland, where appropriate antifungal therapies were initiated and wide débridements were undertaken without success. His clinical status deteriorated, and he died. Tissue examination revealed systemic invasive mucormycosis and aspergillosis. CONCLUSION: The suspicion of invasive fungal infections must be tested early if intervention is to be curative.
BACKGROUND: Invasive mucormycosis or aspergillosis is a life-threatening infection. The disease typically occurs in immunocompromised patients (e.g., those with diabetes mellitus or burns) but is rarely serious in otherwise-healthy young traumapatients. METHODS: Case report and literature review. RESULTS: A previously-healthy 22-year-old United States Marine who sustained large soft tissue injuries in support of Operation Enduring Freedom underwent multiple operations in theater to stabilize his wounds. He was evacuated first to Landstuhl Regional Medical Center in Germany and thence to the National Naval Medical Center in Maryland, where appropriate antifungal therapies were initiated and wide débridements were undertaken without success. His clinical status deteriorated, and he died. Tissue examination revealed systemic invasive mucormycosis and aspergillosis. CONCLUSION: The suspicion of invasive fungal infections must be tested early if intervention is to be curative.
Authors: Tyler E Warkentien; Faraz Shaikh; Amy C Weintrob; Carlos J Rodriguez; Clinton K Murray; Bradley A Lloyd; Anuradha Ganesan; Deepak Aggarwal; M Leigh Carson; David R Tribble Journal: J Clin Microbiol Date: 2015-05-13 Impact factor: 5.948
Authors: E J Kyriopoulos; A Kyriakopoulos; A Karonidis; A Gravvanis; I Gamatsi; C Tsironis; D Tsoutsos Journal: Ann Burns Fire Disasters Date: 2015-12-31
Authors: Ret Carlos J Rodriguez; Anuradha Ganesan; Faraz Shaikh; M Leigh Carson; William Bradley; Tyler E Warkentien; David R Tribble Journal: Mil Med Date: 2022-05-04 Impact factor: 1.563
Authors: Carlos Rodriguez; Amy C Weintrob; James R Dunne; Allison B Weisbrod; Bradley Lloyd; Tyler Warkentien; Debra Malone; Justin Wells; Clinton K Murray; William Bradley; Faraz Shaikh; Jinesh Shah; Michelle Leigh Carson; Deepak Aggarwal; David R Tribble Journal: J Trauma Acute Care Surg Date: 2014-11 Impact factor: 3.313
Authors: Louis R Lewandowski; Amy C Weintrob; David R Tribble; Carlos J Rodriguez; Joseph Petfield; Bradley A Lloyd; Clinton K Murray; Daniel Stinner; Deepak Aggarwal; Faraz Shaikh; Benjamin K Potter Journal: J Orthop Trauma Date: 2016-03 Impact factor: 2.512
Authors: Carlos J Rodriguez; Amy C Weintrob; Jinesh Shah; Debra Malone; James R Dunne; Allison B Weisbrod; Bradley A Lloyd; Tyler E Warkentien; Clinton K Murray; Kenneth Wilkins; Faraz Shaikh; M Leigh Carson; Deepak Aggarwal; David R Tribble Journal: Surg Infect (Larchmt) Date: 2014-05-12 Impact factor: 2.150
Authors: A C Weintrob; A B Weisbrod; J R Dunne; C J Rodriguez; D Malone; B A Lloyd; T E Warkentien; J Wells; C K Murray; W Bradley; F Shaikh; J Shah; D Aggarwal; M L Carson; D R Tribble Journal: Epidemiol Infect Date: 2014-03-18 Impact factor: 4.434