BACKGROUND AND PURPOSE: Heterogeneity of acquisition and postprocessing parameters for magnetic resonance- and computed tomography-based perfusion imaging in acute stroke may limit comparisons between studies, but the current degree of heterogeneity in the literature has not been precisely defined. METHODS: We examined articles published before August 30, 2009 that reported perfusion thresholds, average lesion perfusion values, or correlations of perfusion deficit volumes from acute stroke patients <24 hours postictus. We compared acquisition parameters from published studies with guidance from the Acute Stroke Imaging Research Roadmap(1). In addition, we assessed the consistency of postprocessing parameters. RESULTS: Twenty computed tomography perfusion and 49 perfusion-weighted imaging studies were included from 7152 articles. Although certain parameters were reported frequently, consistently, and in line with the Roadmap proposals, we found substantial heterogeneity in other parameters, and there was considerable variation and underreporting of postprocessing methodology. CONCLUSIONS: There is substantial scope to increase homogeneity in future studies, eg, through reporting standards.
BACKGROUND AND PURPOSE: Heterogeneity of acquisition and postprocessing parameters for magnetic resonance- and computed tomography-based perfusion imaging in acute stroke may limit comparisons between studies, but the current degree of heterogeneity in the literature has not been precisely defined. METHODS: We examined articles published before August 30, 2009 that reported perfusion thresholds, average lesion perfusion values, or correlations of perfusion deficit volumes from acute strokepatients <24 hours postictus. We compared acquisition parameters from published studies with guidance from the Acute Stroke Imaging Research Roadmap(1). In addition, we assessed the consistency of postprocessing parameters. RESULTS: Twenty computed tomography perfusion and 49 perfusion-weighted imaging studies were included from 7152 articles. Although certain parameters were reported frequently, consistently, and in line with the Roadmap proposals, we found substantial heterogeneity in other parameters, and there was considerable variation and underreporting of postprocessing methodology. CONCLUSIONS: There is substantial scope to increase homogeneity in future studies, eg, through reporting standards.
Authors: R Bourcier; S Volpi; B Guyomarch; B Daumas-Duport; A Lintia-Gaultier; C Papagiannaki; J M Serfaty; H Desal Journal: AJNR Am J Neuroradiol Date: 2015-08-27 Impact factor: 3.825
Authors: N D Forkert; P Kaesemann; A Treszl; S Siemonsen; B Cheng; H Handels; J Fiehler; G Thomalla Journal: AJNR Am J Neuroradiol Date: 2013-03-28 Impact factor: 3.825
Authors: Felipe De Los Rios; Dawn O Kleindorfer; Amy Guzik; Santiago Ortega-Gutierrez; Navdeep Sangha; Gyanendra Kumar; James C Grotta; Jin-Moo Lee; Brett C Meyer; Lee H Schwamm; Pooja Khatri Journal: J Stroke Cerebrovasc Dis Date: 2014-08-10 Impact factor: 2.136
Authors: Brooks D Lindsey; Sarah E Shelton; K Heath Martin; Kathryn A Ozgun; Juan D Rojas; F Stuart Foster; Paul A Dayton Journal: Ann Biomed Eng Date: 2016-11-10 Impact factor: 3.934
Authors: Branko N Huisa; William P Neil; Ronald Schrader; Marcel Maya; Benedict Pereira; Nhu T Bruce; Patrick D Lyden Journal: J Stroke Cerebrovasc Dis Date: 2012-12-14 Impact factor: 2.136