| Literature DB >> 21989052 |
J Wouter Jukema1, Tarek A N Ahmed, Jeffrey J W Verschuren, Paul H A Quax.
Abstract
The techniques and materials used during percutaneous coronary intervention have advanced considerably over the past 3 decades, yet restenosis remains one of the major drawbacks of this procedure. Many innovative technologies, including drug-eluting stents, with or without specific polymers, and fully biodegradable stents have been and continue to be developed in the search for a safe and effective antirestenosis therapy. Remarkable advances in stent design and nanoparticle delivery systems ('nanovehicles') have already fueled revolutionary changes in the prevention and treatment of in-stent restenosis. In this Review we provide an overview of the latest innovations for optimizing outcomes of coronary stenting, and up-to-date information about prevention and treatment of in-stent restenosis.Entities:
Mesh:
Year: 2011 PMID: 21989052 DOI: 10.1038/nrcardio.2011.148
Source DB: PubMed Journal: Nat Rev Cardiol ISSN: 1759-5002 Impact factor: 32.419