Literature DB >> 21987596

A novel route to synthesize libraries of quinoxalines via Petasis methodology in two synthetic operations.

Muhammad Ayaz1, Justin Dietrich, Christopher Hulme.   

Abstract

This communication reveals an innovative and facile procedure to prepare quinoxalines in two synthetic steps. The microwave assisted Petasis reaction is followed by the acid mediated unmasking of an internal amino nucleophile, cyclodehydration and oxidation to give collections of quinoxalines in good to excellent yields.

Entities:  

Year:  2011        PMID： 21987596      PMCID： PMC3189012          DOI： 10.1016/j.tetlet.2011.06.115

Source DB:  PubMed          Journal:  Tetrahedron Lett        ISSN： 0040-4039            Impact factor:   2.415


  16 in total

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