Literature DB >> 21986937

Antibody recognition of fluorinated MUC1 glycopeptide antigens.

Thomas Oberbillig1, Christian Mersch, Sarah Wagner, Anja Hoffmann-Röder.   

Abstract

The syntheses of various fluorinated MUC1 glycopeptide antigens and their specific binding to serum antibodies from mice immunized with natural and fluorinated TF(6)-MUC1-TTox conjugate vaccines are presented. This journal is © The Royal Society of Chemistry 2012

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Year:  2011        PMID： 21986937     DOI： 10.1039/c1cc15139h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  10 in total

1.  Chemoenzymatic synthesis of mono- and di-fluorinated Thomsen-Friedenreich (T) antigens and their sialylated derivatives.

Authors:  Jun Yan; Xi Chen; Fengshan Wang; Hongzhi Cao
Journal:  Org Biomol Chem       Date:  2012-12-14       Impact factor: 3.876

2.  A cancer therapeutic vaccine based on clustered Tn-antigen mimetics induces strong antibody-mediated protective immunity.

Authors:  Barbara Richichi; Baptiste Thomas; Michele Fiore; Rosa Bosco; Huma Qureshi; Cristina Nativi; Olivier Renaudet; Lbachir BenMohamed
Journal:  Angew Chem Int Ed Engl       Date:  2014-08-28       Impact factor: 15.336

3.  Synthesis and biological evaluation of a novel MUC1 glycopeptide conjugate vaccine candidate comprising a 4'-deoxy-4'-fluoro-Thomsen-Friedenreich epitope.

Authors:  Manuel Johannes; Maximilian Reindl; Bastian Gerlitzki; Edgar Schmitt; Anja Hoffmann-Röder
Journal:  Beilstein J Org Chem       Date:  2015-01-23       Impact factor: 2.883

4.  Mucin architecture behind the immune response: design, evaluation and conformational analysis of an antitumor vaccine derived from an unnatural MUC1 fragment.

Authors:  Nuria Martínez-Sáez; Nitin T Supekar; Margreet A Wolfert; Iris A Bermejo; Ramón Hurtado-Guerrero; Juan L Asensio; Jesús Jiménez-Barbero; Jesús H Busto; Alberto Avenoza; Geert-Jan Boons; Jesús M Peregrina; Francisco Corzana
Journal:  Chem Sci       Date:  2015-12-15       Impact factor: 9.825

Review 5.  Bioisosteres of Carbohydrate Functional Groups in Glycomimetic Design.

Authors:  Rachel Hevey
Journal:  Biomimetics (Basel)       Date:  2019-07-28

6.  Fluorine effect in nucleophilic fluorination at C4 of 1,6-anhydro-2,3-dideoxy-2,3-difluoro-β-D-hexopyranose.

Authors:  Danny Lainé; Vincent Denavit; Olivier Lessard; Laurie Carrier; Charles-Émile Fecteau; Paul A Johnson; Denis Giguère
Journal:  Beilstein J Org Chem       Date:  2020-11-25       Impact factor: 2.883

Review 7.  Toward Glycomaterials with Selectivity as Well as Affinity.

Authors:  Sarah-Jane Richards; Matthew I Gibson
Journal:  JACS Au       Date:  2021-10-11

8.  The Effect of Deoxyfluorination on Intermolecular Interactions in the Crystal Structures of 1,6-Anhydro-2,3-epimino-hexopyranoses.

Authors:  Martin Jakubec; Ivana Císařová; Jindřich Karban; Jan Sýkora
Journal:  Molecules       Date:  2022-01-03       Impact factor: 4.411

9.  Introducing affinity and selectivity into galectin-targeting nanoparticles with fluorinated glycan ligands.

Authors:  Sarah-Jane Richards; Tessa Keenan; Jean-Baptiste Vendeville; David E Wheatley; Harriet Chidwick; Darshita Budhadev; Claire E Council; Claire S Webster; Helene Ledru; Alexander N Baker; Marc Walker; M Carmen Galan; Bruno Linclau; Martin A Fascione; Matthew I Gibson
Journal:  Chem Sci       Date:  2020-11-16       Impact factor: 9.825

10.  Multifunctional Protein Conjugates with Built-in Adjuvant (Adjuvant-Protein-Antigen) as Cancer Vaccines Boost Potent Immune Responses.

Authors:  Jing-Jing Du; Chang-Wei Wang; Wen-Bo Xu; Lian Zhang; Yuan-Kai Tang; Shi-Hao Zhou; Xiao-Fei Gao; Guang-Fu Yang; Jun Guo
Journal:  iScience       Date:  2020-02-24
  10 in total

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