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Literature DB >> 21984370

New insight into praziquantel against various developmental stages of schistosomes.

Abstract

Praziquantel, due to high efficacy, excellent tolerability, few and transient side effects, simple administration, and competitive cost, is virtually the only drug of choice for treatment of human schistosomiasis. Treatment of schistosomiasis has shown great advances with the introduction of the drug into the therapeutic arsenal in areas that are endemic for the parasite. However, the drug presents various efficacies against different developmental stages of schistosomes, appearing an oddity intermitted mode. The present review article reviews the effects and mechanism of action of praziquantel against schistosomes briefly and suggests the research on this oddity phenomenon.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2011 PMID： 21984370 DOI： 10.1007/s00436-011-2670-3

Source DB: PubMed Journal: Parasitol Res ISSN： 0932-0113 Impact factor: 2.289

72 in total

Review 1. Schistosomiasis--a century searching for chemotherapeutic drugs.

Authors: Gabriela Ribeiro-dos-Santos; Sergio Verjovski-Almeida; Luciana C C Leite
Journal: Parasitol Res Date: 2006-04-25 Impact factor: 2.289

Review 2. Food-borne trematode infections of humans in the United States of America.

Authors: Bernard Fried; Amy Abruzzi
Journal: Parasitol Res Date: 2010-03-30 Impact factor: 2.289

3. Schistosome genomes: a wealth of information.

Authors: Joanne P Webster; Guilherme Oliviera; David Rollinson; Charlotte M Gower
Journal: Trends Parasitol Date: 2010-01-18

4. Schistosoma japonicum GSH S-transferase Sj26 is not the molecular target of praziquantel action.

Authors: J L Milhon; R L Thiboldeaux; K Glowac; J W Tracy
Journal: Exp Parasitol Date: 1997-11 Impact factor: 2.011

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Authors: S H Xiao; W J Yue; Y Q Yang; J Q You
Journal: Chin Med J (Engl) Date: 1987-09 Impact factor: 2.628

6. In vivo and in vitro experiments on the effects of praziquantel on Schistosoma mansoni. A light and electron microscopic study.

Authors: H Mehlhorn; B Becker; P Andrews; H Thomas; J K Frenkel
Journal: Arzneimittelforschung Date: 1981

Review 7. Food-borne trematodiasis: current chemotherapy and advances with artemisinins and synthetic trioxolanes.

Authors: Jennifer Keiser; Jürg Utzinger
Journal: Trends Parasitol Date: 2007-10-22

8. Effect of praziquantel on the free living stages of Schistosoma mansoni.

Authors: P Andrews
Journal: Z Parasitenkd Date: 1978-07-03

9. Further study on mefloquine concerning several aspects in experimental treatment of mice and hamsters infected with Schistosoma japonicum.

Authors: Shu-hua Xiao; Jing-yan Mei; Pei-ying Jiao
Journal: Parasitol Res Date: 2009-10-02 Impact factor: 2.289

10. Light and electron microscopic studies on Schistosoma mansoni Granulomas of mouse livers following treatment with praziquantel.

Authors: H Mehlhorn; J K Frenkel; P Andrews; H Thomas
Journal: Tropenmed Parasitol Date: 1982-12

26 in total

Review 1. Praziquantel for Schistosomiasis: Single-Drug Metabolism Revisited, Mode of Action, and Resistance.

Authors: Nuno Vale; Maria João Gouveia; Gabriel Rinaldi; Paul J Brindley; Fátima Gärtner; José M Correia da Costa
Journal: Antimicrob Agents Chemother Date: 2017-04-24 Impact factor: 5.191

2. Still hope for schistosomiasis vaccine.

Authors: Alessandra Ricciardi; Momar Ndao
Journal: Hum Vaccin Immunother Date: 2015 Impact factor: 3.452

Review 3. Susceptibility or resistance of praziquantel in human schistosomiasis: a review.

Authors: Wei Wang; Li Wang; You-Sheng Liang
Journal: Parasitol Res Date: 2012-10-07 Impact factor: 2.289

4. Efficacy of artemether and artesunate in mice infected with praziquantel non-susceptible isolate of Schistosoma japonicum.

Authors: Wei Wang; Tian-Yu Li; Yuan Ji; Guo-Li Qu; Yi-Li Qian; Hong-Jun Li; Jian-Rong Dai; You-Sheng Liang
Journal: Parasitol Res Date: 2013-12-11 Impact factor: 2.289