Jing-Lin Zhang1, Piu Chan. 1. Department of Neurology and Neurobiology, Beijing Institute of Geriatrics and Xuanwu Hospital of the Capital Medical University, #45 Changchun Street, 100053 Beijing, China. littlenumskull@hotmail.com
Abstract
UNLABELLED: The syndromes of Parkinson's disease (PD) have impacts on health-related quality of life (HRQL). The 39-item Parkinson's disease Questionnaire (PDQ-39) was the first specific and a consistent instrument for the evaluation of HRQL in PD patients. PURPOSE: To test the reliability and validity of Chinese version PDQ-39. METHODS: Hundred and twenty-six PD without cognitive impairment were enrolled. The Chinese version of SF-36 was used to evaluate the congruent validity of PDQ-39 between related domains. Both PDQ-39 and SF-36 scales were fulfilled by the patients themselves. RESULTS: Five of eight subscales of PDQ-39 met the acceptable standards of reliability (Cronbach's α coefficient >0.80), while the other three subscales (cognition, communication, and bodily discomfort) failed to reach the above standards as reported by the others. All the item-to-subscale correlations (range: 0.457-0.887) met the minimal acceptable item convergent validity criterion of 0.40 (P < 0.001). Correlation between PDQ-39 subscales and scales of the SF-36 had high negative correlations with a range of -0.759 to -0.124. Four of them had significant negative correlations (P < 0.0001). CONCLUSIONS: The Chinese version of PDQ-39 is a reliable and valid instrument for Chinese PD patients. It is recommended as the most appropriate HRQL tool for PD.
UNLABELLED: The syndromes of Parkinson's disease (PD) have impacts on health-related quality of life (HRQL). The 39-item Parkinson's disease Questionnaire (PDQ-39) was the first specific and a consistent instrument for the evaluation of HRQL in PDpatients. PURPOSE: To test the reliability and validity of Chinese version PDQ-39. METHODS: Hundred and twenty-six PD without cognitive impairment were enrolled. The Chinese version of SF-36 was used to evaluate the congruent validity of PDQ-39 between related domains. Both PDQ-39 and SF-36 scales were fulfilled by the patients themselves. RESULTS: Five of eight subscales of PDQ-39 met the acceptable standards of reliability (Cronbach's α coefficient >0.80), while the other three subscales (cognition, communication, and bodily discomfort) failed to reach the above standards as reported by the others. All the item-to-subscale correlations (range: 0.457-0.887) met the minimal acceptable item convergent validity criterion of 0.40 (P < 0.001). Correlation between PDQ-39 subscales and scales of the SF-36 had high negative correlations with a range of -0.759 to -0.124. Four of them had significant negative correlations (P < 0.0001). CONCLUSIONS: The Chinese version of PDQ-39 is a reliable and valid instrument for Chinese PDpatients. It is recommended as the most appropriate HRQL tool for PD.
Authors: Seyed-Mohammad Fereshtehnejad; Nader Naderi; Arash Rahmani; Gholam Ali Shahidi; Ahmad Delbari; Johan Lökk Journal: Health Qual Life Outcomes Date: 2014-05-20 Impact factor: 3.186