Literature DB >> 21980256

Establishing a multicentre clinical research network: lessons learned.

N A Hagen1, C R Stiles, P D Biondo, G G Cummings, R L Fainsinger, D E Moulin, J L Pereira, R Spice.   

Abstract

BACKGROUND: Within many health care disciplines, research networks have emerged to connect researchers who are physically separated, to facilitate sharing of expertise and resources, and to exchange valuable skills. A multicentre research network committed to studying difficult cancer pain problems was launched in 2004 as part of a Canadian initiative to increase palliative and end-of-life care research capacity. Funding was received for 5 years to support network activities.
METHODS: Mid-way through the 5-year granting period, an external review panel provided a formal mid-grant evaluation. Concurrently, an internal evaluation of the network by survey of its members was conducted. Based on feedback from both evaluations and on a review of the literature, we identified several components believed to be relevant to the development of a successful clinical cancer research network.
RESULTS: THESE COMMON ELEMENTS OF SUCCESSFUL CLINICAL CANCER RESEARCH NETWORKS WERE IDENTIFIED: shared vision, formal governance policies and terms of reference, infrastructure support, regular and effective communication, an accountability framework, a succession planning strategy to address membership change over time, multiple strategies to engage network members, regular review of goals and timelines, and a balance between structure and creativity.
CONCLUSIONS: In establishing and conducting a multi-year, multicentre clinical cancer research network, network members were led to reflect on the factors that contributed most to the achievement of network goals. Several specific factors were identified that seemed to be highly relevant in promoting success. These observations are presented to foster further discussion on the successful design and operation of research networks.

Entities:  

Keywords:  Clinical cancer research; collaboration; multicentre; network evaluation; research network

Year:  2011        PMID: 21980256      PMCID: PMC3185906          DOI: 10.3747/co.v18i5.814

Source DB:  PubMed          Journal:  Curr Oncol        ISSN: 1198-0052            Impact factor:   3.677


  21 in total

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2.  Partnership synergy: a practical framework for studying and strengthening the collaborative advantage.

Authors:  R D Lasker; E S Weiss; R Miller
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3.  Measuring and improving performance in multicenter research consortia.

Authors:  Sarah M Greene; Gene Hart; Edward H Wagner
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4.  Developing effective interuniversity partnerships and community-based research to address health disparities.

Authors:  Timothy S Carey; Daniel L Howard; Moses Goldmon; James T Roberson; Paul A Godley; Alice Ammerman
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Review 5.  Infrastructure requirements for practice-based research networks.

Authors:  Lee A Green; Linda L White; Henry C Barry; Donald E Nease; Brenda L Hudson
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6.  Models of inter-institutional collaboration to build research capacity for reducing health disparities.

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7.  The practice-based research network as a model for end-of-life care research: challenges and opportunities.

Authors:  Jean S Kutner; Deborah S Main; John M Westfall; Wilson Pace
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Review 8.  Building a research consortium of large health systems: the Cancer Research Network.

Authors:  Edward H Wagner; Sarah M Greene; Gene Hart; Terry S Field; Suzanne Fletcher; Ann M Geiger; Lisa J Herrinton; Mark C Hornbrook; Christine C Johnson; Judy Mouchawar; Sharon J Rolnick; Victor J Stevens; Stephen H Taplin; Dennis Tolsma; Thomas M Vogt
Journal:  J Natl Cancer Inst Monogr       Date:  2005

9.  Collaborative Pediatric Critical Care Research Network (CPCCRN).

Authors:  Douglas F Willson; J Michael Dean; Christopher Newth; Murray Pollack; K J S Anand; Kathleen Meert; Joseph Carcillo; Jerry Zimmerman; Carol Nicholson
Journal:  Pediatr Crit Care Med       Date:  2006-07       Impact factor: 3.624

10.  The Prevention Research Centers Healthy Aging Research Network.

Authors:  Jason E Lang; Lynda Anderson; James LoGerfo; Joseph Sharkey; Elaine Belansky; Lucinda Bryant; Tom Prohaska; Mary Altpeter; Victor Marshall; William Satariano; Susan Ivey; Constance Bayles; Delores Pluto; Sara Wilcox; R Turner Goins; Robert C Byrd
Journal:  Prev Chronic Dis       Date:  2005-12-15       Impact factor: 2.830

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Authors:  Allison C Needham; Mufiza Z Kapadia; Martin Offringa
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2.  Implementation of cardovascular cell therapy network trials: challenges, innovation and lessons learned from experience in the CCTRN.

Authors:  Ki E Park; Lemuel A Moyé; Timothy D Henry; Emerson C Perin; Shelly L Sayre; Judy Bettencourt; Rachel W Vojvodic; Rachel E Olson; Carl J Pepine
Journal:  Expert Rev Cardiovasc Ther       Date:  2013-10-23

3.  Accelerating regulatory progress in multi-institutional research.

Authors:  Andrea R Paolino; Sherry Lee Lauf; Lisa E Pieper; Jared Rowe; Ileana M Vargas; Melissa A Goff; Matthew F Daley; Leah Tuzzio; John F Steiner
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4.  Sustaining Research Networks: the Twenty-Year Experience of the HMO Research Network.

Authors:  John F Steiner; Andrea R Paolino; Ella E Thompson; Eric B Larson
Journal:  EGEMS (Wash DC)       Date:  2014-06-09

5.  Activities supporting the growth of Clinical Trial Networks in Australia.

Authors:  Fiona Nemeh; Rachelle Buchbinder; Carmel M Hawley; Mark R Nelson; Jacqui G Waterkeyn; Christopher M Reid
Journal:  Trials       Date:  2022-01-28       Impact factor: 2.279

6.  Research activities in general medicine: a scoping survey by the Internal Medicine Society of Australia and New Zealand.

Authors:  Ar K Aung; Robert Pickles; Anne Knight; Leigh-Anne Shannon; Andrew Bowers; Sinead Donnelly; Douglas F Johnson; Ian A Scott; Elizabeth L Potter
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7.  Assessing the challenges of multi-scope clinical research sites: an example from NIH HIV/AIDS clinical trials networks.

Authors:  Scott R Rosas; Marie T Cope; Christie Villa; Mahnaz Motevalli; Jill Utech; Jeffrey T Schouten
Journal:  J Eval Clin Pract       Date:  2013-11-13       Impact factor: 2.431

  7 in total

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