Literature DB >> 21975603

Nanoparticle encapsulated silver carbene complexes and their antimicrobial and anticancer properties: a perspective.

Wiley J Youngs1, Amanda R Knapp, Patrick O Wagers, Claire A Tessier.   

Abstract

This perspective discusses the uses of silver for both antimicrobial and anticancer applications. It focuses on the synthesis of silver N-heterocyclic carbene complexes (SCCs) and their in vitro efficacy against a broad spectrum of bacteria, as well as their antitumor properties. Finally, different polymeric nanoparticles are discussed as delivery vehicles for the encapsulation of SCCs and other therapeutic agents for use in vivo.

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Year:  2011        PMID： 21975603     DOI： 10.1039/c1dt11100k

Source DB:  PubMed          Journal:  Dalton Trans        ISSN： 1477-9226            Impact factor:   4.390


  11 in total

1.  Preparation and in vitro antimicrobial activity of silver-bearing degradable polymeric nanoparticles of polyphosphoester-block-poly(L-lactide).

Authors:  Young H Lim; Kristin M Tiemann; Gyu Seong Heo; Patrick O Wagers; Yohannes H Rezenom; Shiyi Zhang; Fuwu Zhang; Wiley J Youngs; David A Hunstad; Karen L Wooley
Journal:  ACS Nano       Date:  2015-01-26       Impact factor: 15.881

2.  Synthesis and molecular structure of biologically significant bis(1,3-dimesityl-4,5-naphthoquinoimidazol-2-ylidene)gold(I) complexes with chloride and dichloridoaurate counter-ions.

Authors:  Jayaraman Selvakumar; Meredith H Miles; David A Grossie; Kuppuswamy Arumugam
Journal:  Acta Crystallogr C Struct Chem       Date:  2019-03-26       Impact factor: 1.172

3.  Pegylated-polycaprolactone nano-sized drug delivery platforms loaded with biocompatible silver(i) complexes for anticancer therapeutics.

Authors:  Despoina Varna; Evi Christodoulou; Eleni Gounari; Chrysanthi Pinelopi Apostolidou; Georgios Landrou; Rigini Papi; George Koliakos; Athanassios G Coutsolelos; Dimitrios N Bikiaris; Panagiotis A Angaridis
Journal:  RSC Med Chem       Date:  2022-05-26

4.  Polymer encapsulation of anticancer silver-N-heterocyclic carbene complexes.

Authors:  H A Mohamed; M Khuphe; S J Boardman; S Shepherd; R M Phillips; P D Thornton; C E Willans
Journal:  RSC Adv       Date:  2018-03-15       Impact factor: 4.036

5.  The use of 111Ag as a tool for studying biological distribution of silver-based antimicrobials.

Authors:  Tolulope A Aweda; Oluwatayo Ikotun; Tara Mastren; Carolyn L Cannon; Brian Wright; Wiley J Youngs; Cathy Cutler; James Guthrie; Suzanne E Lapi
Journal:  Medchemcomm       Date:  2013-06-01       Impact factor: 3.597

6.  Anti-tumor activity of lipophilic imidazolium salts on select NSCLC cell lines.

Authors:  Brian D Wright; Michael C Deblock; Patrick O Wagers; Ernest Duah; Nikki K Robishaw; Kerri L Shelton; Marie R Southerland; Michael A DeBord; Kortney M Kersten; Lucas J McDonald; Jason A Stiel; Matthew J Panzner; Claire A Tessier; Sailaja Paruchuri; Wiley J Youngs
Journal:  Med Chem Res       Date:  2015-02-13       Impact factor: 1.965

7.  An organometallic structure-activity relationship study reveals the essential role of a Re(CO)3 moiety in the activity against gram-positive pathogens including MRSA.

Authors:  Malay Patra; Michaela Wenzel; Pascal Prochnow; Vanessa Pierroz; Gilles Gasser; Julia E Bandow; Nils Metzler-Nolte
Journal:  Chem Sci       Date:  2014-10-13       Impact factor: 9.825

Review 8.  Recent Developments in the Medicinal Applications of Silver-NHC Complexes and Imidazolium Salts.

Authors:  Nicholas A Johnson; Marie R Southerland; Wiley J Youngs
Journal:  Molecules       Date:  2017-07-27       Impact factor: 4.411

9.  A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation.

Authors:  Thanh Q Bui; Huynh Thi Phuong Loan; Tran Thi Ai My; Duong Tuan Quang; Bui Thi Phuong Thuy; Vo Duy Nhan; Phan Tu Quy; Pham Van Tat; Duy Quang Dao; Nguyen Tien Trung; Lam K Huynh; Nguyen Thi Ai Nhung
Journal:  RSC Adv       Date:  2020-08-21       Impact factor: 4.036

10.  Apoptotic efficacy of biogenic silver nanoparticles on human breast cancer MCF-7 cell lines.

Authors:  Jannathul Firdhouse M; Lalitha P
Journal:  Prog Biomater       Date:  2015-10-23
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