Literature DB >> 21972847

Effect of chlorhexidine on denture biofilm accumulation.

Ingrid Machado de Andrade1, Patricia C Cruz, Cláudia H Silva-Lovato, Raphael F de Souza, Maria Cristina Monteiro Souza-Gugelmin, Helena de Freitas Oliveira Paranhos.   

Abstract

PURPOSE: Adequate denture hygiene can prevent and treat infection in edentulous patients, who are frequently elderly and have difficulty brushing their teeth. This study evaluated the efficacy of complete denture biofilm removal using a chlorhexidine solution in two concentrations: 0.12% and 2.0%.
MATERIALS AND METHODS: Sixty complete denture wearers participated in a trial for 21 days after receiving brushing instructions. They were distributed into three groups, according to the tested solution and regimen (n = 20): (G1) Control (daily overnight soaking in water); (G2) daily immersion at home in 0.12% chlorhexidine for 20 minutes after dinner; and (G3) a single immersion in 2.0% chlorhexidine for 5 minutes at the end of the experimental period, performed by a professional. Biofilm coverage area (%) was quantified on the internal surface of maxillary dentures at baseline and after 21 days. Afterward, the differences between initial and posttreatment results were compared by means of the Kruskal-Wallis test (α= 0.05).
RESULTS: Median values for biofilm coverage area after treatment were: (G1) 36.0%; (G2) 5.3%; and (G3) 1.4%. Differences were significant (KW = 35.25; p < 0.001), although G2 and G3 presented similar efficacy in terms of biofilm removal.
CONCLUSIONS: Both chlorhexidine-based treatments had a similar ability to remove denture biofilm. Immersion in 0.12% or 2.0% chlorhexidine solutions can be used as an auxiliary method for cleaning complete dentures.
© 2011 by the American College of Prosthodontists.

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Year:  2011        PMID: 21972847     DOI: 10.1111/j.1532-849X.2011.00774.x

Source DB:  PubMed          Journal:  J Prosthodont        ISSN: 1059-941X            Impact factor:   2.752


  10 in total

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Journal:  Clin Oral Investig       Date:  2015-04-22       Impact factor: 3.573

2.  The effect of chlorhexidine in reducing oral colonisation in geriatric patients: a randomised controlled trial.

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Authors:  Shima Ghasemi; Amir Reza Babaloo; Mahsa Taghizadeh; Yousef Kananizadeh; Mehrnaz Sheikholeslami
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10.  In vitro antifungal evaluation of seven different disinfectants on acrylic resins.

Authors:  A Z Yildirim-Bicer; I Peker; G Akca; I Celik
Journal:  Biomed Res Int       Date:  2014-06-05       Impact factor: 3.411

  10 in total

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