Literature DB >> 21965334

Heterogeneity in breast cancer.

Kornelia Polyak1.   

Abstract

Breast cancer is a heterogeneous disease. There is a high degree of diversity between and within tumors as well as among cancer-bearing individuals, and all of these factors together determine the risk of disease progression and therapeutic resistance. Advances in technologies such as whole-genome sequencing and functional viability screens now allow us to analyze tumors at unprecedented depths. However, translating this increasing knowledge into clinical practice remains a challenge in part due to tumor evolution driven by the diversity of cancer cell populations and their microenvironment. The articles in this Review series discuss recent advances in our understanding of breast tumor heterogeneity, therapies tailored based on this knowledge, and future ways of assessing and treating heterogeneous tumors.

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Year:  2011        PMID： 21965334      PMCID： PMC3195489          DOI： 10.1172/JCI60534

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


  34 in total

Review 1.  A genetic model for colorectal tumorigenesis.

Authors:  E R Fearon; B Vogelstein
Journal:  Cell       Date:  1990-06-01       Impact factor: 41.582

2.  Prospective identification of tumorigenic breast cancer cells.

Authors:  Muhammad Al-Hajj; Max S Wicha; Adalberto Benito-Hernandez; Sean J Morrison; Michael F Clarke
Journal:  Proc Natl Acad Sci U S A       Date:  2003-03-10       Impact factor: 11.205

3.  Molecular portraits of human breast tumours.

Authors:  C M Perou; T Sørlie; M B Eisen; M van de Rijn; S S Jeffrey; C A Rees; J R Pollack; D T Ross; H Johnsen; L A Akslen; O Fluge; A Pergamenschikov; C Williams; S X Zhu; P E Lønning; A L Børresen-Dale; P O Brown; D Botstein
Journal:  Nature       Date:  2000-08-17       Impact factor: 49.962

4.  A cell initiating human acute myeloid leukaemia after transplantation into SCID mice.

Authors:  T Lapidot; C Sirard; J Vormoor; B Murdoch; T Hoang; J Caceres-Cortes; M Minden; B Paterson; M A Caligiuri; J E Dick
Journal:  Nature       Date:  1994-02-17       Impact factor: 49.962

5.  BRCA1 regulates human mammary stem/progenitor cell fate.

Authors:  Suling Liu; Christophe Ginestier; Emmanuelle Charafe-Jauffret; Hailey Foco; Celina G Kleer; Sofia D Merajver; Gabriela Dontu; Max S Wicha
Journal:  Proc Natl Acad Sci U S A       Date:  2008-01-29       Impact factor: 11.205

6.  Comparative lesion sequencing provides insights into tumor evolution.

Authors:  Siân Jones; Wei-Dong Chen; Giovanni Parmigiani; Frank Diehl; Niko Beerenwinkel; Tibor Antal; Arne Traulsen; Martin A Nowak; Christopher Siegel; Victor E Velculescu; Kenneth W Kinzler; Bert Vogelstein; Joseph Willis; Sanford D Markowitz
Journal:  Proc Natl Acad Sci U S A       Date:  2008-03-12       Impact factor: 11.205

Review 7.  Breast cancer: origins and evolution.

Authors:  Kornelia Polyak
Journal:  J Clin Invest       Date:  2007-11       Impact factor: 14.808

8.  The genomic landscapes of human breast and colorectal cancers.

Authors:  Laura D Wood; D Williams Parsons; Siân Jones; Jimmy Lin; Tobias Sjöblom; Rebecca J Leary; Dong Shen; Simina M Boca; Thomas Barber; Janine Ptak; Natalie Silliman; Steve Szabo; Zoltan Dezso; Vadim Ustyanksky; Tatiana Nikolskaya; Yuri Nikolsky; Rachel Karchin; Paul A Wilson; Joshua S Kaminker; Zemin Zhang; Randal Croshaw; Joseph Willis; Dawn Dawson; Michail Shipitsin; James K V Willson; Saraswati Sukumar; Kornelia Polyak; Ben Ho Park; Charit L Pethiyagoda; P V Krishna Pant; Dennis G Ballinger; Andrew B Sparks; James Hartigan; Douglas R Smith; Erick Suh; Nickolas Papadopoulos; Phillip Buckhaults; Sanford D Markowitz; Giovanni Parmigiani; Kenneth W Kinzler; Victor E Velculescu; Bert Vogelstein
Journal:  Science       Date:  2007-10-11       Impact factor: 47.728

9.  Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer.

Authors:  Aleix Prat; Joel S Parker; Olga Karginova; Cheng Fan; Chad Livasy; Jason I Herschkowitz; Xiaping He; Charles M Perou
Journal:  Breast Cancer Res       Date:  2010-09-02       Impact factor: 6.466

10.  Efficient tumour formation by single human melanoma cells.

Authors:  Elsa Quintana; Mark Shackleton; Michael S Sabel; Douglas R Fullen; Timothy M Johnson; Sean J Morrison
Journal:  Nature       Date:  2008-12-04       Impact factor: 49.962
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  338 in total

1.  Progress in breast cancer research.

Authors:  Kornelia Polyak; Peter K Vogt
Journal:  Proc Natl Acad Sci U S A       Date:  2012-02-13       Impact factor: 11.205

2.  Sacrificial Bioprinting of a Mammary Ductal Carcinoma Model.

Authors:  Margaux Duchamp; Tingting Liu; Anne M van Genderen; Vanessa Kappings; Rahmi Oklu; Leif W Ellisen; Yu Shrike Zhang
Journal:  Biotechnol J       Date:  2019-05-27       Impact factor: 4.677

Review 3.  Review of quantitative multiscale imaging of breast cancer.

Authors:  Michael A Pinkert; Lonie R Salkowski; Patricia J Keely; Timothy J Hall; Walter F Block; Kevin W Eliceiri
Journal:  J Med Imaging (Bellingham)       Date:  2018-01-22

Review 4.  Emerging evidence for the role of differential tumor microenvironment in breast cancer racial disparity: a closer look at the surroundings.

Authors:  Sachin Kumar Deshmukh; Sanjeev K Srivastava; Nikhil Tyagi; Aamir Ahmad; Ajay P Singh; Ahmed A L Ghadhban; Donna L Dyess; James E Carter; Kari Dugger; Seema Singh
Journal:  Carcinogenesis       Date:  2017-08-01       Impact factor: 4.944

5.  MAEL Cancer-Testis Antigen as a Diagnostic Marker in Primary Stages of Gastric Cancer with Helicobacter pylori Infection.

Authors:  Mohammad Reza Abbaszadegan; Negin Taghehchian; Azadeh Aarabi; Meysam Moghbeli
Journal:  J Gastrointest Cancer       Date:  2020-03

6.  Loss of FBP1 by Snail-mediated repression provides metabolic advantages in basal-like breast cancer.

Authors:  Chenfang Dong; Tingting Yuan; Yadi Wu; Yifan Wang; Teresa W M Fan; Sumitra Miriyala; Yiwei Lin; Jun Yao; Jian Shi; Tiebang Kang; Pawel Lorkiewicz; Daret St Clair; Mien-Chie Hung; B Mark Evers; Binhua P Zhou
Journal:  Cancer Cell       Date:  2013-02-28       Impact factor: 31.743

7.  Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis.

Authors:  Ting Wang; Daniele M Gilkes; Naoharu Takano; Lisha Xiang; Weibo Luo; Corey J Bishop; Pallavi Chaturvedi; Jordan J Green; Gregg L Semenza
Journal:  Proc Natl Acad Sci U S A       Date:  2014-06-17       Impact factor: 11.205

Review 8.  Co-expression in Single-Cell Analysis: Saving Grace or Original Sin?

Authors:  Megan Crow; Jesse Gillis
Journal:  Trends Genet       Date:  2018-08-23       Impact factor: 11.639

9.  Mitochondrial complex I activity and NAD+/NADH balance regulate breast cancer progression.

Authors:  Antonio F Santidrian; Akemi Matsuno-Yagi; Melissa Ritland; Byoung B Seo; Sarah E LeBoeuf; Laurie J Gay; Takao Yagi; Brunhilde Felding-Habermann
Journal:  J Clin Invest       Date:  2013-02-15       Impact factor: 14.808

10.  Inference of tumor evolution during chemotherapy by computational modeling and in situ analysis of genetic and phenotypic cellular diversity.

Authors:  Vanessa Almendro; Yu-Kang Cheng; Amanda Randles; Shalev Itzkovitz; Andriy Marusyk; Elisabet Ametller; Xavier Gonzalez-Farre; Montse Muñoz; Hege G Russnes; Aslaug Helland; Inga H Rye; Anne-Lise Borresen-Dale; Reo Maruyama; Alexander van Oudenaarden; Mitchell Dowsett; Robin L Jones; Jorge Reis-Filho; Pere Gascon; Mithat Gönen; Franziska Michor; Kornelia Polyak
Journal:  Cell Rep       Date:  2014-01-23       Impact factor: 9.423
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