Literature DB >> 21962185

Two-stage reconstruction of head and neck defects after tumor resection with a dermal regeneration template.

Moritz Felcht1, Wolfgang Koenen, Gunther Sassmann, Sergij Goerdt, Jörg Faulhaber.   

Abstract

BACKGROUND: Large defects after tumor resection in the head and neck area can be reconstructed with local flaps or skin grafts or heal by secondary intention. Especially in elderly patients, a rapid procedure with an acceptable aesthetic and reliable functional outcome is required.
OBJECTIVE: We investigated an alternative strategy using the Integra Dermal Regeneration Template (IDRT) for the reconstruction of large defects.
METHODS: In 18 patients (75 ± 3 years), 19 extended head and neck defects were treated with IDRT to enhance healing.
RESULTS: The mean defect size was 32 ± 7 cm2. The defects were transplanted within a mean postoperative time of 25 ± 2 days and overall showed good cosmetic results and stable scars. The mean follow-up time was 11 ± 1 months. Minor complications were hyperpigmentation (n  =  1), small ulcus (n  =  1), one minor ectropion (n  =  1), and partial loss of the skin graft after immediate radiotherapy (n  =  1). In one patient, the silicon layer had to be removed after 8 days owing to partial destruction of the IDRT. We observed shrinkage of 50 ± 4% within 6 months.
CONCLUSION: IDRT is an alternative technique for the reconstruction of extended head and neck defects. It can be conducted without major complications and with a short healing time and acceptable cosmetic results in elderly patients.

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Year:  2011        PMID: 21962185     DOI: 10.2310/7750.2011.10050

Source DB:  PubMed          Journal:  J Cutan Med Surg        ISSN: 1203-4754            Impact factor:   2.092


  5 in total

Review 1.  Skin cancers and dermal substitutes: Is it safe? Review of the literature and presentation of a 2-stage surgical protocol for the treatment of non-melanoma skin cancers of the head in fragile patients.

Authors:  Marco Marcasciano; Marco Mazzocchi; Juste Kaciulyte; Noemi Spissu; Donato Casella; Diego Ribuffo; Luca Andrea Dessy
Journal:  Int Wound J       Date:  2018-06-04       Impact factor: 3.315

2.  Reconstruction following Excision of Malignant Scalp Tumors with Split Thickness Skin Graft with and without Acellular Dermal Matrix: A Comparative Study.

Authors:  Javad Rahmati; Soheil Boroumand; Koroush Ghanbarzadeh; Shahriar Haddady Abianeh; Hojjat Molaei; Afshin Fathi; Arjang Ghahremani; Omid Etemad
Journal:  J Cutan Aesthet Surg       Date:  2019 Oct-Dec

3.  Malignant Skin Cancer Excision in Combined Therapy with Electro-Chemotherapy and Dermal Substitute.

Authors:  Barbara De Angelis; Alberto Balzani; Alessia Pagnotta; Eleonora Tati; Fabrizio Orlandi; Margarida Fernandes Lopes Morais D'Autilio; Valerio Cervelli; Pietro Gentile
Journal:  Curr Oncol       Date:  2021-05-05       Impact factor: 3.677

4.  One-Stage Reconstruction of Scalp after Full-Thickness Oncologic Defects Using a Dermal Regeneration Template (Integra).

Authors:  Barbara De Angelis; Pietro Gentile; Eleonora Tati; Davide J Bottini; Ilaria Bocchini; Fabrizio Orlandi; Giampiero Pepe; Chiara Di Segni; Giulio Cervelli; Valerio Cervelli
Journal:  Biomed Res Int       Date:  2015-11-16       Impact factor: 3.411

5.  The Use of Integra Dermal Regeneration Template Versus Flaps for Reconstruction of Full-Thickness Scalp Defects Involving the Calvaria: A Cost-Benefit Analysis.

Authors:  M Schiavon; M Francescon; D Drigo; G Salloum; R Baraziol; J Tesei; E Fraccalanza; F Barbone
Journal:  Aesthetic Plast Surg       Date:  2016-10-03       Impact factor: 2.326

  5 in total

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