Literature DB >> 21956432

Thirty-day outcomes in patients treated with en bloc colectomy and pancreatectomy for locally advanced carcinoma of the colon.

Ian M Paquette1, Brian R Swenson, Mary R Kwaan, Anders F Mellgren, Robert D Madoff.   

Abstract

OBJECTIVE: The aim of this was to define 30-day outcomes of patients treated with colectomy and en bloc pancreatectomy for invasive colon cancer.
METHODS: ACS NSQIP was used to identify patients who underwent colectomy and pancreatectomy concomitantly (n = 65) for colon carcinoma. Patients with en bloc pancreatectomy were compared to a propensity score-matched control group for 30-day outcomes.
RESULTS: Sixteen patients underwent a pancreaticoduodenectomy with colectomy and 49 patients underwent a distal pancreatectomy with colectomy. There were 195 matched control patients. En bloc pancreatectomy (Whipple vs. distal pancreatectomy vs. control) patients had longer OR times (390 vs. 265 vs.137 min) and length of postoperative stay (12 vs. 10 vs. 6 days). The frequency of pulmonary complications (31.3% vs. 36.7% vs. 3.6%), blood transfusions (2.9 vs. 1.7 vs. 0.3 U), wound dehiscence, (18.8% vs. 6.12% vs.0.5%) and surgical site infection (43.5% vs. 34.7% vs.14.9%) were substantially higher in the pancreatectomy group (p < 0.05). There were no statistically significant differences in 30-day mortality between the pancreatectomy group and the control group (6.3% vs. 0% vs. 1.5% p = 0.25)
CONCLUSIONS: Perioperative outcomes with en bloc pancreatectomy and colectomy include increased pulmonary complications, blood transfusions, wound complications, and length of stay compared to patients treated with colectomy alone for colon cancer.

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Mesh:

Year:  2011        PMID: 21956432     DOI: 10.1007/s11605-011-1691-7

Source DB:  PubMed          Journal:  J Gastrointest Surg        ISSN: 1091-255X            Impact factor:   3.452


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  6 in total

1.  Combined pancreaticoduodenectomy and colon resection for locally advanced peri-ampullary tumours: analysis of peri-operative morbidity and mortality.

Authors:  Sara J Temple; Peter T W Kim; Pablo E Serrano; Daniel Kagedan; Sean P Cleary; Carol-Anne Moulton; Ian D McGilvray; Steven Gallinger; Paul D Greig; Alice C Wei
Journal:  HPB (Oxford)       Date:  2014-04-18       Impact factor: 3.647

2.  Indication for en bloc pancreatectomy with colectomy: when is it safe?

Authors:  Patrick B Schwartz; Alexandra M Roch; Jane S Han; Alex V Vaicius; William P Lancaster; E Molly Kilbane; Michael G House; Nicholas J Zyromski; C Max Schmidt; Atilla Nakeeb; Eugene P Ceppa
Journal:  Surg Endosc       Date:  2017-06-29       Impact factor: 4.584

3.  Drain Contamination after Distal Pancreatectomy: Incidence, Risk Factors, and Association with Postoperative Pancreatic Fistula.

Authors:  Feng Yang; Chen Jin; Sijie Hao; Deliang Fu
Journal:  J Gastrointest Surg       Date:  2019-02-27       Impact factor: 3.452

Review 4.  Pancreatoduodenectomy associated with colonic resections: indications, pitfalls, and outcomes.

Authors:  Tommaso Giuliani; Anthony Di Gioia; Stefano Andrianello; Giovanni Marchegiani; Claudio Bassi
Journal:  Updates Surg       Date:  2021-02-13

5.  En Bloc Pancreaticoduodenectomy for Locally Advanced Right Colon Cancers.

Authors:  Cihan Ağalar; Aras Emre Canda; Tarkan Unek; Selman Sokmen
Journal:  Int J Surg Oncol       Date:  2017-07-02

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Authors:  Kosei Takagi; Takahito Yagi; Yuzo Umeda; Ryuichi Yoshida; Daisuke Nobuoka; Takashi Kuise; Kenjiro Kumano; Takeshi Kojima; Takuro Fushimi; Toshiyoshi Fujiwara
Journal:  Int J Surg Case Rep       Date:  2017-08-08
  6 in total

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