Literature DB >> 21948036

Survival after pathological fractures of the proximal femur.

Martyn J Parker1, Asif Z Khan, Tom K Rowlands.   

Abstract

We report on the survival of 145 patients presenting to a single centre with a pathological metastatic fracture of the proximal femur. The single surviving patient had a follow-up of 17.7 years. Mean survival for the 144 patients who died was 332 days (range 2 to 3053 days), being longest for those with myeloma (662 days), lymphoma (> 633 days) and breast tumours (477 days) and lowest for lung tumours (110 days). The most common sites for the primary tumour were breast (36%), prostate (23%) and lung (17%). 47% of fractures were intracapsular, 28% trochanteric and 25% subtrochanteric. 99% of the fractures were treated surgically with a mean hospital stay of 19 days. The commonest fracture healing complication was further fracture of the femur around or immediately below the implant which occurred after 9/144 (6.2%) of operations. The difference in survival of patients related to the primary tumour site is of relevance in planning surgical treatment and discussing prognosis with patients.

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Year:  2011        PMID: 21948036     DOI: 10.5301/HIP.2011.8654

Source DB:  PubMed          Journal:  Hip Int        ISSN: 1120-7000            Impact factor:   2.135


  7 in total

1.  Internal fixation versus endoprosthetic replacement of the proximal femur for metastatic bone disease: Single institutional outcomes.

Authors:  Charles A Gusho; Bishir Clayton; Nabil Mehta; Wassim Hmeidan; Matthew W Colman; Steven Gitelis; Alan T Blank
Journal:  J Orthop       Date:  2021-11-08

2.  Metastatic bone disease: Have we improved after a decade of guidelines?

Authors:  P Harvie; D Whitwell
Journal:  Bone Joint Res       Date:  2013-06-01       Impact factor: 5.853

3.  The role of postoperative radiation and coordination of care in patients with metastatic bone disease of the appendicular skeleton.

Authors:  Andrew R Summers; Travis Philipp; Jacob D Mikula; Kenneth R Gundle
Journal:  Orthop Rev (Pavia)       Date:  2018-02-16

4.  Percutaneous internal fixation with Y-STRUT® device to prevent both osteoporotic and pathological hip fractures: a prospective pilot study.

Authors:  François H Cornelis; Lambros Tselikas; Thibault Carteret; Bruno Lapuyade; Thierry De Baere; Jean Charles Le Huec; Frédéric Deschamps
Journal:  J Orthop Surg Res       Date:  2017-02-09       Impact factor: 2.359

Review 5.  Prevention of Pathological Fracture of the Proximal Femur: A Systematic Review of Surgical and Percutaneous Image-Guided Techniques Used in Interventional Oncology.

Authors:  Laëtitia Rodrigues; François H Cornelis; Nicolas Reina; Sylvie Chevret
Journal:  Medicina (Kaunas)       Date:  2019-11-22       Impact factor: 2.430

6.  Inflammatory conversion of quiescent osteoblasts by metastatic breast cancer cells through pERK1/2 aggravates cancer-induced bone destruction.

Authors:  Jungho Back; Minh Nam Nguyen; Lu Li; Saelim Lee; Inkyu Lee; Fancheng Chen; Lauren Gillinov; Yeon-Ho Chung; Kareme D Alder; Hyuk-Kwon Kwon; Kristin E Yu; Christopher M Dussik; Zichen Hao; Michael J Flores; Yoseph Kim; Izuchukwu K Ibe; Alana M Munger; Sung Wook Seo; Francis Y Lee
Journal:  Bone Res       Date:  2021-09-29       Impact factor: 13.362

7.  Hip Fracture Prevention in Osteoporotic Elderly and Cancer Patients: An On-Line French Survey Evaluating Current Needs.

Authors:  Laëtitia Rodrigues; François H Cornelis; Sylvie Chevret
Journal:  Medicina (Kaunas)       Date:  2020-08-07       Impact factor: 2.430

  7 in total

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