Literature DB >> 21943460

Prophylaxis of venous thromboembolism in general surgery: guidelines differ and we still need local policies.

D Veeramootoo1, L Harrower, R Saunders, D Robinson, W B Campbell.   

Abstract

INTRODUCTION: Venous thromboembolism (VTE) prophylaxis has become a major issue for surgeons both in the UK and worldwide. Several different sources of guidance on VTE prophylaxis are available but these differ in design and detail.
METHODS: Two similar audits were performed, one year apart, on the VTE prophylaxis prescribed for all general surgical inpatients during a single week (90 patients and 101 patients). Classification of patients into different risk groups and compliance in prescribing prophylaxis were examined using different international, national and local guidelines.
RESULTS: There were significant differences between the numbers of patients in high, moderate and low-risk groups according to the different guidelines. When groups were combined to indicate simply 'at risk' or 'not at risk' (in the manner of one of the guidelines), then differences were not significant. Our compliance improved from the first audit to the second. Patients at high risk received VTE prophylaxis according to guidance more consistently than those at low risk.
CONCLUSIONS: Differences in guidance on VTE prophylaxis can affect compliance significantly when auditing practice, depending on the choice of 'gold standard'. National guidance does not remove the need for clear and detailed local policies. Making decisions about policies for lower-risk patients can be more difficult than for those at high risk.

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Year:  2011        PMID: 21943460      PMCID: PMC3365454          DOI: 10.1308/003588411X580926

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  15 in total

1.  Efficacy and safety of enoxaparin versus unfractionated heparin for prevention of deep vein thrombosis in elective cancer surgery: a double-blind randomized multicentre trial with venographic assessment. ENOXACAN Study Group.

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Journal:  Br J Surg       Date:  1997-08       Impact factor: 6.939

2.  Prevention and treatment of venous thromboembolism. International Consensus Statement (guidelines according to scientific evidence).

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Journal:  Int Angiol       Date:  2006-06       Impact factor: 2.789

Review 3.  Thrombosis and coagulation: deep vein thrombosis and pulmonary embolism prophylaxis.

Authors:  Daniel A Anaya; Avery B Nathens
Journal:  Surg Clin North Am       Date:  2005-12       Impact factor: 2.741

4.  Risk-based evaluation of thromboprophylaxis among surgical inpatients: are low risk patients treated unnecessarily?

Authors:  G Roche-Nagle; J Curran; D J Bouchier-Hayes; S Tierney
Journal:  Ir J Med Sci       Date:  2007-06-07       Impact factor: 1.568

5.  Incorrect use of thromboprophylaxis for venous thromboembolism in medical and surgical patients: results of a multicentric, observational and cross-sectional study in Brazil.

Authors:  D Deheinzelin; A L Braga; L C Martins; M A Martins; A Hernandez; W B Yoshida; F Maffei; M Monachini; D Calderaro; W Campos; G T Sguizzatto; B Caramelli
Journal:  J Thromb Haemost       Date:  2006-06       Impact factor: 5.824

Review 6.  Prevention of venous thromboembolism: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.

Authors:  William H Geerts; Graham F Pineo; John A Heit; David Bergqvist; Michael R Lassen; Clifford W Colwell; Joel G Ray
Journal:  Chest       Date:  2004-09       Impact factor: 9.410

Review 7.  Low molecular weight heparin for the prevention of venous thromboembolism after abdominal surgery.

Authors:  D Bergqvist
Journal:  Br J Surg       Date:  2004-08       Impact factor: 6.939

8.  Low molecular weight heparin started before surgery as prophylaxis against deep vein thrombosis: 2500 versus 5000 XaI units in 2070 patients.

Authors:  D Bergqvist; U S Burmark; P A Flordal; J Frisell; T Hallböök; M Hedberg; A Horn; E Kelty; P Kvitting; A Lindhagen
Journal:  Br J Surg       Date:  1995-04       Impact factor: 6.939

Review 9.  Assessing, preventing, and treating venous thromboembolism: evidence-based approaches.

Authors:  Edith A Nutescu
Journal:  Am J Health Syst Pharm       Date:  2007-06-01       Impact factor: 2.637

10.  Venous thromboembolism risk and prophylaxis in the acute hospital care setting (ENDORSE study): a multinational cross-sectional study.

Authors:  Alexander T Cohen; Victor F Tapson; Jean-Francois Bergmann; Samuel Z Goldhaber; Ajay K Kakkar; Bruno Deslandes; Wei Huang; Maksim Zayaruzny; Leigh Emery; Frederick A Anderson
Journal:  Lancet       Date:  2008-02-02       Impact factor: 79.321

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  1 in total

Review 1.  The effect of information technology intervention on using appropriate VTE prophylaxis in non-surgical patients: A systematic review and meta-analysis.

Authors:  Mehrdad Karajizadeh; Soheil Hassanipour; Roxana Sharifian; Fatemeh Tajbakhsh; Hamid Reza Saeidnia
Journal:  Digit Health       Date:  2022-08-17
  1 in total

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