Literature DB >> 21934671

Peli1 (rel)ieves autoimmunity.

Paul N Moynagh.   

Abstract

T cell tolerance is essential to the prevention of autoimmunity. The ubiquitin E3 ligase Peli1 acts as a negative regulator of T cell activation and contributes to the maintenance of self-tolerance.

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Year:  2011        PMID： 21934671     DOI： 10.1038/ni.2108

Source DB:  PubMed          Journal:  Nat Immunol        ISSN： 1529-2908            Impact factor:   25.606


  11 in total

1.  Nuclear factor-kappaB modulates regulatory T cell development by directly regulating expression of Foxp3 transcription factor.

Authors:  Meixiao Long; Sung-Gyoo Park; Ian Strickland; Matthew S Hayden; Sankar Ghosh
Journal:  Immunity       Date:  2009-12-18       Impact factor: 31.745

Review 2.  Cbl-b and itch: key regulators of peripheral T-cell tolerance.

Authors:  K Venuprasad
Journal:  Cancer Res       Date:  2010-04-15       Impact factor: 12.701

Review 3.  Cellular and genetic mechanisms of self tolerance and autoimmunity.

Authors:  Christopher C Goodnow; Jonathon Sprent; Barbara Fazekas de St Groth; Carola G Vinuesa
Journal:  Nature       Date:  2005-06-02       Impact factor: 49.962

4.  Smad6 negatively regulates interleukin 1-receptor-Toll-like receptor signaling through direct interaction with the adaptor Pellino-1.

Authors:  Kyung-Chul Choi; Youn Sook Lee; Seunghwan Lim; Hyo Kyoung Choi; Chang-Hun Lee; Eun-Kyung Lee; Suntaek Hong; In-Hoo Kim; Seong-Jin Kim; Seok Hee Park
Journal:  Nat Immunol       Date:  2006-09-03       Impact factor: 25.606

5.  Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production.

Authors:  Mikyoung Chang; Wei Jin; Shao-Cong Sun
Journal:  Nat Immunol       Date:  2009-09-06       Impact factor: 25.606

6.  BCL10 mediates lipopolysaccharide/toll-like receptor-4 signaling through interaction with Pellino2.

Authors:  Yingle Liu; Wei Dong; Lu Chen; Rong Xiang; Huazhong Xiao; Gejing De; Zhimin Wang; Yipeng Qi
Journal:  J Biol Chem       Date:  2004-06-22       Impact factor: 5.157

Review 7.  The Pellino family: IRAK E3 ligases with emerging roles in innate immune signalling.

Authors:  Paul N Moynagh
Journal:  Trends Immunol       Date:  2008-11-18       Impact factor: 16.687

Review 8.  Regulation and function of NF-kappaB transcription factors in the immune system.

Authors:  Sivakumar Vallabhapurapu; Michael Karin
Journal:  Annu Rev Immunol       Date:  2009       Impact factor: 28.527

9.  The role of TBK1 and IKKε in the expression and activation of Pellino 1.

Authors:  Hilary Smith; Xin-Yu Liu; Liang Dai; Eddy T H Goh; Aye-Thu Chan; Jiajia Xi; Cheah-Chen Seh; Insaf A Qureshi; Julien Lescar; Christiane Ruedl; Robert Gourlay; Simon Morton; Joanne Hough; Edward G McIver; Philip Cohen; Peter C F Cheung
Journal:  Biochem J       Date:  2011-03-15       Impact factor: 3.857

10.  The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity.

Authors:  Mikyoung Chang; Wei Jin; Jae-Hoon Chang; Yichuan Xiao; George C Brittain; Jiayi Yu; Xiaofei Zhou; Yi-Hong Wang; Xuhong Cheng; Pingwei Li; Brian A Rabinovich; Patrick Hwu; Shao-Cong Sun
Journal:  Nat Immunol       Date:  2011-08-28       Impact factor: 25.606
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  6 in total

1.  Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis.

Authors:  Shuo Yang; Bingwei Wang; Fiachra Humphries; Ruaidhri Jackson; Marc E Healy; Ronan Bergin; Gabriella Aviello; Barry Hall; Deirdre McNamara; Trevor Darby; Aoife Quinlan; Fergus Shanahan; Silvia Melgar; Padraic G Fallon; Paul N Moynagh
Journal:  Nat Immunol       Date:  2013-07-28       Impact factor: 25.606

Review 2.  The roles of Pellino E3 ubiquitin ligases in immunity.

Authors:  Paul N Moynagh
Journal:  Nat Rev Immunol       Date:  2014-01-21       Impact factor: 53.106

3.  Pellino 1 promotes lymphomagenesis by deregulating BCL6 polyubiquitination.

Authors:  Hye-Young Park; Heounjeong Go; Ha Rim Song; Suhyeon Kim; Geun-Hyoung Ha; Yoon-Kyung Jeon; Ji-Eun Kim; Ho Lee; Hyeseong Cho; Ho Chul Kang; Hee-Young Chung; Chul-Woo Kim; Doo Hyun Chung; Chang-Woo Lee
Journal:  J Clin Invest       Date:  2014-10-08       Impact factor: 14.808

4.  Pellino3 targets the IRF7 pathway and facilitates autoregulation of TLR3- and viral-induced expression of type I interferons.

Authors:  Jakub Siednienko; Ruaidhri Jackson; Mark Mellett; Nezira Delagic; Shuo Yang; Bingwei Wang; Lisa S Tang; John J Callanan; Bernard P Mahon; Paul N Moynagh
Journal:  Nat Immunol       Date:  2012-10-07       Impact factor: 25.606

5.  The E3 ubiquitin ligase Pellino2 mediates priming of the NLRP3 inflammasome.

Authors:  Fiachra Humphries; Ronan Bergin; Ruaidhri Jackson; Nezira Delagic; Bingwei Wang; Shuo Yang; Alice V Dubois; Rebecca J Ingram; Paul N Moynagh
Journal:  Nat Commun       Date:  2018-04-19       Impact factor: 14.919

6.  miR-21 and Pellino-1 Expression Profiling in Autoimmune Premature Ovarian Insufficiency.

Authors:  Xinran Li; Jiaxin Xie; Qingru Wang; Huihua Cai; Chuhai Xie; Xiafei Fu
Journal:  J Immunol Res       Date:  2020-04-13       Impact factor: 4.818
  6 in total

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