| Literature DB >> 2193231 |
K F Stringer1, C J Ingles, J Greenblatt.
Abstract
The potent transactivation domain of the herpes simplex virion protein VP16 was used as a column ligand for affinity chromatography. VP16 binds strongly and highly selectively to the human and yeast TATA box-binding factors. Our results imply that the principal target for acidic activation domains is the TATA-box factor TFIID.Entities:
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Year: 1990 PMID: 2193231 DOI: 10.1038/345783a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962