Literature DB >> 2193231

Direct and selective binding of an acidic transcriptional activation domain to the TATA-box factor TFIID.

K F Stringer1, C J Ingles, J Greenblatt.   

Abstract

The potent transactivation domain of the herpes simplex virion protein VP16 was used as a column ligand for affinity chromatography. VP16 binds strongly and highly selectively to the human and yeast TATA box-binding factors. Our results imply that the principal target for acidic activation domains is the TATA-box factor TFIID.

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Year:  1990        PMID: 2193231     DOI: 10.1038/345783a0

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  274 in total

1.  A role of transcriptional activators as antirepressors for the autoinhibitory activity of TATA box binding of transcription factor IID.

Authors:  T Kotani; K Banno; M Ikura; A G Hinnebusch; Y Nakatani; M Kawaichi; T Kokubo
Journal:  Proc Natl Acad Sci U S A       Date:  2000-06-20       Impact factor: 11.205

2.  An activation-specific role for transcription factor TFIIB in vivo.

Authors:  W H Wu; M Hampsey
Journal:  Proc Natl Acad Sci U S A       Date:  1999-03-16       Impact factor: 11.205

3.  The yeast protein Xtc1 functions as a direct transcriptional repressor.

Authors:  Ana Traven; Lidija Staresincić; Milica Arnerić; Mary Sopta
Journal:  Nucleic Acids Res       Date:  2002-06-01       Impact factor: 16.971

4.  Molecular characterization of an acidic region deletion mutant of Cockayne syndrome group B protein.

Authors:  M Sunesen; R R Selzer; R M Brosh; A S Balajee; T Stevnsner; V A Bohr
Journal:  Nucleic Acids Res       Date:  2000-08-15       Impact factor: 16.971

5.  The VP16 paradox: herpes simplex virus VP16 contains a long-range activation domain but within the natural multiprotein complex activates only from promoter-proximal positions.

Authors:  M Hagmann; O Georgiev; W Schaffner
Journal:  J Virol       Date:  1997-08       Impact factor: 5.103

6.  Differences in determinants required for complex formation and transactivation in related VP16 proteins.

Authors:  M Grapes; P O'Hare
Journal:  J Virol       Date:  2000-11       Impact factor: 5.103

7.  Evidence for the involvement of the Glc7-Reg1 phosphatase and the Snf1-Snf4 kinase in the regulation of INO1 transcription in Saccharomyces cerevisiae.

Authors:  M K Shirra; K M Arndt
Journal:  Genetics       Date:  1999-05       Impact factor: 4.562

8.  A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator.

Authors:  R Yagi; L F Chen; K Shigesada; Y Murakami; Y Ito
Journal:  EMBO J       Date:  1999-05-04       Impact factor: 11.598

9.  Requirements for activation of the herpes simplex virus glycoprotein C promoter in vitro by the viral regulatory protein ICP4.

Authors:  B Gu; N DeLuca
Journal:  J Virol       Date:  1994-12       Impact factor: 5.103

10.  Yeast coactivator MBF1 mediates GCN4-dependent transcriptional activation.

Authors:  K Takemaru; S Harashima; H Ueda; S Hirose
Journal:  Mol Cell Biol       Date:  1998-09       Impact factor: 4.272

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