Bioreducible micelles and hydrogels with tunable properties from multi-armed biodegradable copolymers.

Multi-armed biodegradable block copolymers with a bioreducible core mPCL-b-PEO were for the first time synthesized by thiol-yne click chemistry. They self-assembled into bioreducible micelles and hydrogels in aqueous solution, which demonstrated tunable size, mechanical and drug-release properties. This journal is © The Royal Society of Chemistry 2011