Literature DB >> 21929033

Bright solitary waves in malignant gliomas.

Víctor M Pérez-García1, Gabriel F Calvo, Juan Belmonte-Beitia, David Diego, Luis Pérez-Romasanta.   

Abstract

We put forward a nonlinear wave model describing the fundamental dynamical features of an aggressive type of brain tumors. Our model accounts for the invasion of normal tissue by a proliferating and propagating rim of active glioma cancer cells in the tumor boundary and the subsequent formation of a necrotic core. By resorting to numerical simulations, phase space analysis, and exact solutions we prove that bright solitary tumor waves develop in such systems. Possible implications of our model as a tool to extract relevant patient specific tumor parameters in combination with standard preoperative clinical imaging are also discussed.

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Year:  2011        PMID: 21929033     DOI: 10.1103/PhysRevE.84.021921

Source DB:  PubMed          Journal:  Phys Rev E Stat Nonlin Soft Matter Phys        ISSN: 1539-3755


  11 in total

1.  A mesoscopic simulator to uncover heterogeneity and evolutionary dynamics in tumors.

Authors:  Juan Jiménez-Sánchez; Álvaro Martínez-Rubio; Anton Popov; Julián Pérez-Beteta; Youness Azimzade; David Molina-García; Juan Belmonte-Beitia; Gabriel F Calvo; Víctor M Pérez-García
Journal:  PLoS Comput Biol       Date:  2021-02-10       Impact factor: 4.475

2.  Morphologic Features on MR Imaging Classify Multifocal Glioblastomas in Different Prognostic Groups.

Authors:  J Pérez-Beteta; D Molina-García; M Villena; M J Rodríguez; C Velásquez; J Martino; B Meléndez-Asensio; Á Rodríguez de Lope; R Morcillo; J M Sepúlveda; A Hernández-Laín; A Ramos; J A Barcia; P C Lara; D Albillo; A Revert; E Arana; V M Pérez-García
Journal:  AJNR Am J Neuroradiol       Date:  2019-03-28       Impact factor: 3.825

3.  Glioblastoma: does the pre-treatment geometry matter? A postcontrast T1 MRI-based study.

Authors:  Julián Pérez-Beteta; Alicia Martínez-González; David Molina; Mariano Amo-Salas; Belén Luque; Elena Arregui; Manuel Calvo; José M Borrás; Carlos López; Marta Claramonte; Juan A Barcia; Lidia Iglesias; Josué Avecillas; David Albillo; Miguel Navarro; José M Villanueva; Juan C Paniagua; Juan Martino; Carlos Velásquez; Beatriz Asenjo; Manuel Benavides; Ismael Herruzo; María Del Carmen Delgado; Ana Del Valle; Anthony Falkov; Philippe Schucht; Estanislao Arana; Luis Pérez-Romasanta; Víctor M Pérez-García
Journal:  Eur Radiol       Date:  2016-06-21       Impact factor: 5.315

4.  A three-dimensional computational analysis of magnetic resonance images characterizes the biological aggressiveness in malignant brain tumours.

Authors:  J Pérez-Beteta; A Martínez-González; V M Pérez-García
Journal:  J R Soc Interface       Date:  2018-12-21       Impact factor: 4.118

5.  Radiation protraction schedules for low-grade gliomas: a comparison between different mathematical models.

Authors:  I Budia; A Alvarez-Arenas; T E Woolley; G F Calvo; J Belmonte-Beitia
Journal:  J R Soc Interface       Date:  2019-12-11       Impact factor: 4.118

6.  Accurate state estimation from uncertain data and models: an application of data assimilation to mathematical models of human brain tumors.

Authors:  Eric J Kostelich; Yang Kuang; Joshua M McDaniel; Nina Z Moore; Nikolay L Martirosyan; Mark C Preul
Journal:  Biol Direct       Date:  2011-12-21       Impact factor: 4.540

7.  A Mathematical Model Coupling Tumor Growth and Angiogenesis.

Authors:  Jiangping Xu; Guillermo Vilanova; Hector Gomez
Journal:  PLoS One       Date:  2016-02-18       Impact factor: 3.240

8.  Geometrical Measures Obtained from Pretreatment Postcontrast T1 Weighted MRIs Predict Survival Benefits from Bevacizumab in Glioblastoma Patients.

Authors:  David Molina; Julián Pérez-Beteta; Alicia Martínez-González; Juan M Sepúlveda; Sergi Peralta; Miguel J Gil-Gil; Gaspar Reynes; Ana Herrero; Ramón De Las Peñas; Raquel Luque; Jaume Capellades; Carmen Balaña; Víctor M Pérez-García
Journal:  PLoS One       Date:  2016-08-24       Impact factor: 3.240

9.  Prognostic models based on imaging findings in glioblastoma: Human versus Machine.

Authors:  David Molina-García; Luis Vera-Ramírez; Julián Pérez-Beteta; Estanislao Arana; Víctor M Pérez-García
Journal:  Sci Rep       Date:  2019-04-12       Impact factor: 4.379

10.  A mathematical model describes the malignant transformation of low grade gliomas: Prognostic implications.

Authors:  Magdalena U Bogdańska; Marek Bodnar; Monika J Piotrowska; Michael Murek; Philippe Schucht; Jürgen Beck; Alicia Martínez-González; Víctor M Pérez-García
Journal:  PLoS One       Date:  2017-08-01       Impact factor: 3.240

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