Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Making sense of glycosphingolipids in epithelial polarity.

Literature DB >> 21926989

Making sense of glycosphingolipids in epithelial polarity.

Abstract

A potential role for glycosphingolipids and lipid rafts in apical sorting was initially met with enthusiasm, but genetic analysis has since provided little support for it. A report now establishes that glycosphingolipids mediate apical sorting, and specifically help maintain apicobasal polarity in Caenorhabditis elegans.

Entities: Chemical Species

Mesh：

Substances：
Glycosphingolipids

Year: 2011 PMID： 21926989 DOI： 10.1038/ncb2350

Source DB: PubMed Journal: Nat Cell Biol ISSN： 1465-7392 Impact factor: 28.824

13 in total

Review 1. Adaptation of core mechanisms to generate cell polarity.

Authors: W James Nelson
Journal: Nature Date: 2003-04-17 Impact factor: 49.962

Review 2. Glycosphingolipids in engineered mice: insights into function.

Authors: Koichi Furukawa; Noriyo Tokuda; Tetsuya Okuda; Orie Tajima; Keiko Furukawa
Journal: Semin Cell Dev Biol Date: 2004-08 Impact factor: 7.727

Review 3. Cell polarity in eggs and epithelia: parallels and diversity.

Authors: Daniel St Johnston; Julie Ahringer
Journal: Cell Date: 2010-05-28 Impact factor: 41.582

Review 4. Apical trafficking in epithelial cells: signals, clusters and motors.

Authors: Ora A Weisz; Enrique Rodriguez-Boulan
Journal: J Cell Sci Date: 2009-12-01 Impact factor: 5.285

Review 5. Functional rafts in cell membranes.

Authors: K Simons; E Ikonen
Journal: Nature Date: 1997-06-05 Impact factor: 49.962

6. Cell surface polarization during yeast mating.

Authors: Michel Bagnat; Kai Simons
Journal: Proc Natl Acad Sci U S A Date: 2002-10-08 Impact factor: 11.205

7. Ceramide regulates atypical PKCzeta/lambda-mediated cell polarity in primitive ectoderm cells. A novel function of sphingolipids in morphogenesis.

Authors: Kannan Krishnamurthy; Guanghu Wang; Jeane Silva; Brian G Condie; Erhard Bieberich
Journal: J Biol Chem Date: 2006-11-14 Impact factor: 5.157

Review 2. Lipid rafts and neurodegeneration: structural and functional roles in physiologic aging and neurodegenerative diseases.

Authors: Sara Grassi; Paola Giussani; Laura Mauri; Simona Prioni; Sandro Sonnino; Alessandro Prinetti
Journal: J Lipid Res Date: 2019-12-23 Impact factor: 5.922

2 in total

Making sense of glycosphingolipids in epithelial polarity.

Review 1. Adaptation of core mechanisms to generate cell polarity.

Review 2. Glycosphingolipids in engineered mice: insights into function.

Review 3. Cell polarity in eggs and epithelia: parallels and diversity.

Review 4. Apical trafficking in epithelial cells: signals, clusters and motors.

Review 5. Functional rafts in cell membranes.

6. Cell surface polarization during yeast mating.

7. Ceramide regulates atypical PKCzeta/lambda-mediated cell polarity in primitive ectoderm cells. A novel function of sphingolipids in morphogenesis.

Review 8. Molecular regulation of lumen morphogenesis.

9. Loss of galectin-3 impairs membrane polarisation of mouse enterocytes in vivo.

10. Apicobasal domain identities of expanding tubular membranes depend on glycosphingolipid biosynthesis.

Review 1. Polarity in mammalian epithelial morphogenesis.

Review 2. Lipid rafts and neurodegeneration: structural and functional roles in physiologic aging and neurodegenerative diseases.