Xiaobai Ouyang1, Xueqing Huang, Qiuhua Pan, Chenqi Zuo, Cui Huang, Xiangliang Yang, Yanbing Zhao. 1. The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, 237 Luoyu Road, Wuhan 430079, People's Republic of China.
Abstract
OBJECTIVES: To date, the production of highly durable dentine bonding is still a challenge. Self-healing bonding resins may provide a new direction for the improvement of the bonding durability. The objective of the current study was to synthesize polyurethane nanocapsules encapsulated with the core material triethylene glycol dimethacrylate (TEGDMA) for use as a major component in a self-healing bonding resin. METHODS: TEGDMA nanocapsules were synthesized via interfacial polycondensation in a miniemulsion, and the TEGDMA nanocapsules were then characterized via Fourier-transform infrared (FTIR) spectrometer, field emission scanning electron microscopy (FESEM), and high-performance liquid chromatography (HPLC) to investigate the morphology, the average TEGDMA loading (DL%), and encapsulation efficiency (EE%). The mechanical property of dental adhesive with different concentrations (0, 3, 6, 9, and 12 wt%) of the TEGDMA nanocapsules were also measured, and the cytotoxicity was investigated using an MTT assay. RESULTS: FTIR confirmed that the TEGDMA nanocapsules were successfully synthesized. These nanocapsules showed a high drug load. The bond strength of the dental adhesive incorporated with 9 wt% TEGDMA nanocapsules was significantly higher compared with those of the other groups (P<0.001). Moreover, the biocompatibility of the dental adhesive was not affected by the incorporation of the TEGDMA nanocapsules. CONCLUSIONS: The current study demonstrated the successful synthesis of TEGDMA nanocapsules, and the overall properties of the dental adhesive were not compromised. Copyright Â
RCT Entities:
OBJECTIVES: To date, the production of highly durable dentine bonding is still a challenge. Self-healing bonding resins may provide a new direction for the improvement of the bonding durability. The objective of the current study was to synthesize polyurethane nanocapsules encapsulated with the core material triethylene glycol dimethacrylate (TEGDMA) for use as a major component in a self-healing bonding resin. METHODS:TEGDMA nanocapsules were synthesized via interfacial polycondensation in a miniemulsion, and the TEGDMA nanocapsules were then characterized via Fourier-transform infrared (FTIR) spectrometer, field emission scanning electron microscopy (FESEM), and high-performance liquid chromatography (HPLC) to investigate the morphology, the average TEGDMA loading (DL%), and encapsulation efficiency (EE%). The mechanical property of dental adhesive with different concentrations (0, 3, 6, 9, and 12 wt%) of the TEGDMA nanocapsules were also measured, and the cytotoxicity was investigated using an MTT assay. RESULTS: FTIR confirmed that the TEGDMA nanocapsules were successfully synthesized. These nanocapsules showed a high drug load. The bond strength of the dental adhesive incorporated with 9 wt% TEGDMA nanocapsules was significantly higher compared with those of the other groups (P<0.001). Moreover, the biocompatibility of the dental adhesive was not affected by the incorporation of the TEGDMA nanocapsules. CONCLUSIONS: The current study demonstrated the successful synthesis of TEGDMA nanocapsules, and the overall properties of the dental adhesive were not compromised. Copyright Â
Authors: Mostafa Yourdkhani; Ariene Arcas Leme-Kraus; Berdan Aydin; Ana Karina Bedran-Russo; Scott R White Journal: Dent Mater Date: 2017-04-06 Impact factor: 5.304
Authors: Junling Wu; Michael D Weir; Qiang Zhang; Chuanjian Zhou; Mary Anne S Melo; Hockin H K Xu Journal: Dent Mater Date: 2015-12-29 Impact factor: 5.304