Literature DB >> 21922290

Multicomponent synthesis of acylated short peptoids with antifungal activity against plant pathogens.

Matías D Galetti1, Adriana M Cirigliano, Gabriela M Cabrera, Javier A Ramírez.   

Abstract

In this article, we describe the synthesis of a small library of short peptoids composed of four glycine residues and acylated with a fatty acid that showed a remarkable in vitro activity against two fungal plant pathogens. Their straightforward synthesis implied two consecutive Ugi reactions and can be efficiently extended to the construction of highly diverse libraries.

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Year:  2011        PMID: 21922290     DOI: 10.1007/s11030-011-9334-1

Source DB:  PubMed          Journal:  Mol Divers        ISSN: 1381-1991            Impact factor:   2.943


  10 in total

1.  Short alkylated peptoid mimics of antimicrobial lipopeptides.

Authors:  Nathaniel P Chongsiriwatana; Tyler M Miller; Modi Wetzler; Sergei Vakulenko; Amy J Karlsson; Sean P Palecek; Shahriar Mobashery; Annelise E Barron
Journal:  Antimicrob Agents Chemother       Date:  2010-10-18       Impact factor: 5.191

2.  Design and synthesis of an optimized positional scanning library of peptoids: identification of novel multidrug resistance reversal agents.

Authors:  Isabel Masip; Nuria Cortés; Maria-José Abad; Marisa Guardiola; Enrique Pérez-Payá; José Ferragut; Antonio Ferrer-Montiel; Angel Messeguer
Journal:  Bioorg Med Chem       Date:  2005-03-15       Impact factor: 3.641

Review 3.  Recent developments in isocyanide based multicomponent reactions in applied chemistry.

Authors:  Alexander Dömling
Journal:  Chem Rev       Date:  2006-01       Impact factor: 60.622

4.  Supramolecular compounds from multiple ugi multicomponent macrocyclizations: peptoid-based cryptands, cages, and cryptophanes.

Authors:  Daniel G Rivera; Ludger A Wessjohann
Journal:  J Am Chem Soc       Date:  2006-06-07       Impact factor: 15.419

5.  Cyclic peptoids.

Authors:  Sung Bin Y Shin; Barney Yoo; Louis J Todaro; Kent Kirshenbaum
Journal:  J Am Chem Soc       Date:  2007-02-27       Impact factor: 15.419

6.  Design and synthesis of cyclic RGD pentapeptoids by consecutive Ugi reactions.

Authors:  Otilie E Vercillo; Carlos Kleber Z Andrade; Ludger A Wessjohann
Journal:  Org Lett       Date:  2007-12-19       Impact factor: 6.005

Review 7.  Quantification and modeling of crop losses: a review of purposes.

Authors:  Serge Savary; Paul S Teng; Laetitia Willocquet; Forrest W Nutter
Journal:  Annu Rev Phytopathol       Date:  2006       Impact factor: 13.078

8.  Comparing mass spectrometric characteristics of peptides and peptoids.

Authors:  W Heerma; C Versluis; C G de Koster; J A Kruijtzer; I Zigrovic; R M Liskamp
Journal:  Rapid Commun Mass Spectrom       Date:  1996       Impact factor: 2.419

9.  Discovery of nanomolar ligands for 7-transmembrane G-protein-coupled receptors from a diverse N-(substituted)glycine peptoid library.

Authors:  R N Zuckermann; E J Martin; D C Spellmeyer; G B Stauber; K R Shoemaker; J M Kerr; G M Figliozzi; D A Goff; M A Siani; R J Simon
Journal:  J Med Chem       Date:  1994-08-19       Impact factor: 7.446

10.  Kinetics and equilibria of cis/trans isomerization of backbone amide bonds in peptoids.

Authors:  Qiang Sui; Dan Borchardt; Dallas L Rabenstein
Journal:  J Am Chem Soc       Date:  2007-09-07       Impact factor: 15.419

  10 in total
  4 in total

1.  Discovery and Characterization of a Peptoid with Antifungal Activity against Cryptococcus neoformans.

Authors:  Ashley E Corson; Scott A Armstrong; Matthew E Wright; Erin E McClelland; Kevin L Bicker
Journal:  ACS Med Chem Lett       Date:  2016-10-03       Impact factor: 4.345

2.  Improved potency and reduced toxicity of the antifungal peptoid AEC5 through submonomer modification.

Authors:  Madyson P Middleton; Scott A Armstrong; Kevin L Bicker
Journal:  Bioorg Med Chem Lett       Date:  2018-10-03       Impact factor: 2.823

3.  Synthesis of antibacterial 1,3-diyne-linked peptoids from an Ugi-4CR/Glaser coupling approach.

Authors:  Martin C N Brauer; Ricardo A W Neves Filho; Bernhard Westermann; Ramona Heinke; Ludger A Wessjohann
Journal:  Beilstein J Org Chem       Date:  2015-01-07       Impact factor: 2.883

Review 4.  Recent Advances in the Synthesis of Peptoid Macrocycles.

Authors:  Alexandra M Webster; Steven L Cobb
Journal:  Chemistry       Date:  2018-02-21       Impact factor: 5.236

  4 in total

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