INTRODUCTION: Our purpose was to determine whether diffusion-weighted MR imaging (DWI) could be used in differentiation of benign and malign breast lesions. MATERIALS AND METHODS: 41 women patients were included in the study. 45 lesions were diagnosed by biopsy; 25 (55.5%) of these lesions were malignant and 20 (44.5%) were benign. The apparent diffusion coefficient (ADC) values of these lesions were prospectively compared with their histopathological results. RESULTS: Differentiation of the malignant and benign masses revealed that the threshold value of the ADC was 1.0 x 10(-3) mm(2)/s, its sensitivity was demonstrated as 95%, specificity as 100%, positive predictive as 100%, negative predictive as 94% and accuracy rate as 97%. CONCLUSIONS: DWI improves diagnostic accuracy of the conventional breast MRI. ADC measurements may be useful for differentiation of the malign and benign masses.
INTRODUCTION: Our purpose was to determine whether diffusion-weighted MR imaging (DWI) could be used in differentiation of benign and malign breast lesions. MATERIALS AND METHODS: 41 womenpatients were included in the study. 45 lesions were diagnosed by biopsy; 25 (55.5%) of these lesions were malignant and 20 (44.5%) were benign. The apparent diffusion coefficient (ADC) values of these lesions were prospectively compared with their histopathological results. RESULTS: Differentiation of the malignant and benign masses revealed that the threshold value of the ADC was 1.0 x 10(-3) mm(2)/s, its sensitivity was demonstrated as 95%, specificity as 100%, positive predictive as 100%, negative predictive as 94% and accuracy rate as 97%. CONCLUSIONS: DWI improves diagnostic accuracy of the conventional breast MRI. ADC measurements may be useful for differentiation of the malign and benign masses.
Authors: Savannah C Partridge; Christiane D Mullins; Brenda F Kurland; Michael D Allain; Wendy B DeMartini; Peter R Eby; Constance D Lehman Journal: AJR Am J Roentgenol Date: 2010-06 Impact factor: 3.959
Authors: Denise R Aberle; Caroline Chiles; Constanine Gatsonis; Bruce J Hillman; C Daniel Johnson; Bruce L McClennan; Donald G Mitchell; Etta D Pisano; Mitchell D Schnall; A Gregory Sorensen Journal: Radiology Date: 2005-06 Impact factor: 11.105
Authors: Wendie A Berg; Lorena Gutierrez; Moriel S NessAiver; W Bradford Carter; Mythreyi Bhargavan; Rebecca S Lewis; Olga B Ioffe Journal: Radiology Date: 2004-10-14 Impact factor: 11.105
Authors: Guner Sonmez; Ali Kemal Sivrioglu; Murat Velioglu; Mehmet Incedayi; Hasan Soydan; Kemal Kara; Ferhat Ateş; Muzaffer Saglam Journal: Wien Klin Wochenschr Date: 2012-09-17 Impact factor: 1.704