Literature DB >> 21918121

Use of inactivated Escherichia coli enterotoxins to enhance respiratory mucosal adjuvanticity during vaccination in swine.

Roger W Barrette1, Steven M Szczepanek, Debra Rood, Sreerupa Challa, Naomi Avery, Michael Vajdy, Ed Kramer, Luis Rodriguez, Lawrence K Silbart.   

Abstract

In order to augment responses to respiratory vaccines in swine, various adjuvants were intranasally coadministered with a foot-and-mouth disease virus (FMDV) antigen to pigs. Detoxified Escherichia coli enterotoxins LTK63 and LTR72 enhanced antigen-specific mucosal and systemic immunity, demonstrating their efficacy as adjuvants for nonreplicating antigens upon intranasal immunization in swine.

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 21918121      PMCID： PMC3209021          DOI： 10.1128/CVI.05273-11

Source DB:  PubMed          Journal:  Clin Vaccine Immunol        ISSN： 1556-679X


  11 in total

1.  Quantifying specific antibody concentrations by enzyme-linked immunosorbent assay using slope correction.

Authors:  Roger W Barrette; Jessica Urbonas; Lawrence K Silbart
Journal:  Clin Vaccine Immunol       Date:  2006-07

Review 2.  Mucosal delivery of vaccines in domestic animals.

Authors:  Volker Gerdts; George K Mutwiri; Suresh K Tikoo; Lorne A Babiuk
Journal:  Vet Res       Date:  2006-04-14       Impact factor: 3.683

3.  Concomitant delivery of a CTL-restricted peptide antigen and CpG ODN by PLGA microparticles induces cellular immune response.

Authors:  Stefan Fischer; Eva Schlosser; Marc Mueller; Noémi Csaba; Hans P Merkle; Marcus Groettrup; Bruno Gander
Journal:  J Drug Target       Date:  2009-09       Impact factor: 5.121

4.  A novel chitosan CpG nanoparticle regulates cellular and humoral immunity of mice.

Authors:  Kai-Yuan Wu; Mei Wu; Man-Liang Fu; Hui Li; Yi Yang; Huan Zhang; Chi Cheng; Ze-Zhou Wang; Xiu-Ying Wang; Xue-Bing Lü; Di-Guang Liu; Hua Li; Rong Gao
Journal:  Biomed Environ Sci       Date:  2006-04       Impact factor: 3.118

Review 5.  Heat-labile enterotoxins as adjuvants or anti-inflammatory agents.

Authors:  Shuang Liang; George Hajishengallis
Journal:  Immunol Invest       Date:  2010       Impact factor: 3.657

Review 6.  The postnatal development of the mucosal immune system and mucosal tolerance in domestic animals.

Authors:  Mick Bailey; Karin Haverson
Journal:  Vet Res       Date:  2006-04-14       Impact factor: 3.683

Review 7.  The structure of an immunodominant loop on foot and mouth disease virus, serotype O1, determined under reducing conditions.

Authors:  D Rowlands; D Logan; R Abu-Ghazaleh; W Blakemore; S Curry; T Jackson; A King; S Lea; R Lewis; J Newman
Journal:  Arch Virol Suppl       Date:  1994

8.  The adjuvant effect of a non-toxic mutant of heat-labile enterotoxin of Escherichia coli for the induction of measles virus-specific CTL responses after intranasal co-immunization with a synthetic peptide.

Authors:  C D Partidos; M Pizza; R Rappuoli; M W Steward
Journal:  Immunology       Date:  1996-12       Impact factor: 7.397

9.  Mucosal adjuvanticity and immunogenicity of LTR72, a novel mutant of Escherichia coli heat-labile enterotoxin with partial knockout of ADP-ribosyltransferase activity.

Authors:  M M Giuliani; G Del Giudice; V Giannelli; G Dougan; G Douce; R Rappuoli; M Pizza
Journal:  J Exp Med       Date:  1998-04-06       Impact factor: 14.307

10.  A novel bioadhesive intranasal delivery system for inactivated influenza vaccines.

Authors:  M Singh; M Briones; D T O'Hagan
Journal:  J Control Release       Date:  2001-02-23       Impact factor: 9.776
View more
  5 in total

1.  Xenoepitope substitution avoids deceptive imprinting and broadens the immune response to foot-and-mouth disease virus.

Authors:  Steven M Szczepanek; Roger W Barrette; Debra Rood; Diana Alejo; Lawrence K Silbart
Journal:  Clin Vaccine Immunol       Date:  2012-02-08

2.  Chitosan as an adjuvant for a Helicobacter pylori therapeutic vaccine.

Authors:  Yanfeng Gong; Liming Tao; Fucai Wang; Wei Liu; Lei Jing; Dongsheng Liu; Sijun Hu; Yong Xie; Nanjin Zhou
Journal:  Mol Med Rep       Date:  2015-06-17       Impact factor: 2.952

3.  Comparison of immune responses to intranasal and intrapulmonary vaccinations with the attenuated Mycoplasma hyopneumoniae 168 strain in pigs.

Authors:  Pengcheng Li; Yunfeng Li; Guoqing Shao; Qinghua Yu; Qian Yang
Journal:  J Vet Med Sci       Date:  2015-01-30       Impact factor: 1.267

Review 4.  Challenges of Generating and Maintaining Protective Vaccine-Induced Immune Responses for Foot-and-Mouth Disease Virus in Pigs.

Authors:  Nicholas A Lyons; Young S Lyoo; Donald P King; David J Paton
Journal:  Front Vet Sci       Date:  2016-11-30

Review 5.  Review of Newly Identified Functions Associated With the Heat-Labile Toxin of Enterotoxigenic Escherichia coli.

Authors:  Qiangde Duan; Pengpeng Xia; Rahul Nandre; Weiping Zhang; Guoqiang Zhu
Journal:  Front Cell Infect Microbiol       Date:  2019-08-13       Impact factor: 5.293
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.