Literature DB >> 21917934

Air-gas exchange reevaluated: clinically important results of a computer simulation.

Manoharan Shunmugam1, Sudhakaran Shunmugam, Tom H Williamson, D Alistair Laidlaw.   

Abstract

PURPOSE: The primary aim of this study was to evaluate the efficiency of air-gas exchange techniques and the factors that influence the final concentration of an intraocular gas tamponade. Parameters were varied to find the optimum method of performing an air-gas exchange in ideal circumstances.
METHODS: A computer model of the eye was designed using 3D software with fluid flow analysis capabilities. Factors such as angular distance between ports, gas infusion gauge, exhaust vent gauge and depth were varied in the model. Flow rate and axial length were also modulated to simulate faster injections and more myopic eyes, respectively. The flush volume of gas required to achieve a 97% intraocular gas fraction concentration were compared.
RESULTS: Modulating individual factors did not reveal any clinically significant difference in the angular distance between ports, exhaust vent size, and depth or rate of gas injection. In combination, however, there was a 28% increase in air-gas exchange efficiency comparing the most efficient with the least efficient studied parameters in this model. The gas flush volume required to achieve a 97% gas fill also increased proportionately at a ratio of 5.5 to 6.2 times the volume of the eye.
CONCLUSIONS: A 35-mL flush is adequate for eyes up to 25 mm in axial length; however, eyes longer than this would require a much greater flush volume, and surgeons should consider using two separate 50-mL gas syringes to ensure optimal gas concentration for eyes greater than 25 mm in axial length.

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Year:  2011        PMID: 21917934     DOI: 10.1167/iovs.11-8258

Source DB:  PubMed          Journal:  Invest Ophthalmol Vis Sci        ISSN: 0146-0404            Impact factor:   4.799


  5 in total

1.  Gas Expansion Three Days after Pars Plana Vitrectomy with Sulfur Hexafluoride 20% Tamponade following Carbon Monoxide Toxicity and Oxygen Therapy.

Authors:  Mojtaba Abrishami; Mehrdad Motamed Shariati; Ali Bolouki; Ghodsieh Zamani
Journal:  Case Rep Ophthalmol Med       Date:  2022-05-09

2.  Duration of intraocular gases following vitreoretinal surgery.

Authors:  Andreas Kontos; James Tee; Alastair Stuart; Zaid Shalchi; Tom H Williamson
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2016-07-26       Impact factor: 3.117

3.  Measurement of the volume of the vitrectomized space during vitrectomy in myopic patients with retinal detachment.

Authors:  Hidenori Tanaka; Atsuhiro Tanikawa; Yoshiaki Shimada; Yuzo Miyake; Tadashi Mizuguchi; Masayuki Horiguchi
Journal:  Jpn J Ophthalmol       Date:  2020-01-06       Impact factor: 2.447

4.  Intravitreal fluorinated gas preference and occurrence of rare ischemic postoperative complications after pars plana vitrectomy: a survey of the american society of retina specialists.

Authors:  Eric J Sigler; John C Randolph; Steve Charles; Jorge I Calzada
Journal:  J Ophthalmol       Date:  2012-09-11       Impact factor: 1.909

5.  Computational fluid dynamics (CFD) simulation analysis on retinal gas cover rates using computational eye models.

Authors:  Makoto Gozawa; Yoshihiro Takamura; Tomoe Aoki; Kentaro Iwasaki; Masaru Inatani
Journal:  Sci Rep       Date:  2021-03-02       Impact factor: 4.379

  5 in total

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