Literature DB >> 21917697

Epidemiology of syphilis in Kenya: results from a nationally representative serological survey.

Boaz Otieno-Nyunya1, Eddas Bennett, Rebecca Bunnell, Sufia Dadabhai, Anthony Gichangi A, Nelly Mugo, John Wanyungu, Isaack Baya, Reinhard Kaiser.   

Abstract

OBJECTIVES: The authors used data from the Kenya AIDS Indicator Survey (KAIS) 2007 to determine the prevalence of syphilis and associated risk factors among adults aged 15-64 years.
METHODS: KAIS was a nationally representative population-based sero-survey that examined demographic and behavioural indicators and serological testing for syphilis, HIV and herpes simplex virus type 2 (HSV-2) in adults aged 15-64 years. The authors analysed data from 8935 women and 6727 men with complete syphilis results. Logistic regression models stratified by sex were used to assess potential factors associated with syphilis sero-prevalence.
RESULTS: Overall, 262 adults tested positive for syphilis (1.8%, 95% CI 1.5% to 2.1%); sero-prevalence was similar among women and men (1.7%, 95% CI 1.3% to 2.0% and 1.9%, 95% CI 1.5% to 2.3%, respectively). Syphilis prevalence was the highest among men with HIV (6.4%, 95% CI 3.1% to 9.7%) and HSV-2 (4.5%, 95% CI 3.4% to 5.7%) infection. Independent risk factors for syphilis included HIV (men only, adjusted OR (AOR) 3.4, 95% CI 1.6% to 7.1%), HSV-2 (women, AOR 3.5, 95% CI 2.1% to 5.8%; men AOR 2.2, 95% CI 1.3% to 3.7%), lack of male circumcision (AOR 2.2, 95% CI 1.3% to 3.7%), poorest or poorer versus richest wealth index (women, AOR 2.0, 95% CI 1.0% to 4.2%; men AOR 2.5, 95% CI 1.4% to 4.9%) and no primary versus secondary or more education in men (AOR 4.8, 95% CI 2.0% to 11.7%).
CONCLUSIONS: Syphilis prevalence in the general population in Kenya is relatively low and eradication could be possible but would require intensified syphilis prevention and control efforts, including routine screening in HIV, sexually transmitted infection and antenatal care clinics as well as in family planning and male circumcision settings.

Entities:  

Mesh:

Year:  2011        PMID: 21917697     DOI: 10.1136/sextrans-2011-050026

Source DB:  PubMed          Journal:  Sex Transm Infect        ISSN: 1368-4973            Impact factor:   3.519


  14 in total

1.  Uptake of Home-Based Syphilis and Human Immunodeficiency Virus Testing Among Male Partners of Pregnant Women in Western Kenya.

Authors:  Jennifer Mark; John Kinuthia; Alison C Roxby; Daisy Krakowiak; Alfred Osoti; Barbra A Richardson; Molly Ann Gone; Victor Asila; Saloni Parikh; Carey Farquhar
Journal:  Sex Transm Dis       Date:  2017-09       Impact factor: 2.830

2.  Male Partner Linkage to Clinic-Based Services for Sexually Transmitted Infections and Human Immunodeficiency Virus Services Following Couple Home-Based Education and Testing.

Authors:  Jennifer Mark; John Kinuthia; Alfred O Osoti; Molly A Gone; Victor Asila; Daisy Krakowiak; Monisha Sharma; Saloni Parikh; Quy T Ton; Barbra A Richardson; Carey Farquhar; Alison C Roxby
Journal:  Sex Transm Dis       Date:  2019-11       Impact factor: 2.830

3.  Sexually transmitted infections and male circumcision: a systematic review and meta-analysis.

Authors:  Robert S Van Howe
Journal:  ISRN Urol       Date:  2013-04-16

4.  Reduced in vitro doxycycline susceptibility in plasmodium falciparum field isolates from Kenya is associated with PfTetQ KYNNNN sequence polymorphism.

Authors:  Angela O Achieng; Luiser A Ingasia; Dennis W Juma; Agnes C Cheruiyot; Charles A Okudo; Redemptah A Yeda; Jelagat Cheruiyot; Hoseah M Akala; Jacob Johnson; Ben Andangalu; Fredrick Eyase; Walter G Z O Jura; Edwin Kamau
Journal:  Antimicrob Agents Chemother       Date:  2014-07-28       Impact factor: 5.191

5.  Sero-conversion rate of Syphilis and HIV among pregnant women attending antenatal clinic in Tanzania: a need for re-screening at delivery.

Authors:  John D T Lawi; Mariam M Mirambo; Moke Magoma; Martha F Mushi; Hyasinta M Jaka; Balthazary Gumodoka; Stephen E Mshana
Journal:  BMC Pregnancy Childbirth       Date:  2015-01-22       Impact factor: 3.007

6.  Ethical issues evolving from patients' perspectives on compulsory screening for syphilis and voluntary screening for cervical cancer in Kenya.

Authors:  Dickens S Omondi Aduda; Nhlanhla Mkhize
Journal:  BMC Med Ethics       Date:  2014-03-28       Impact factor: 2.652

Review 7.  The Global Epidemiology of Syphilis in the Past Century - A Systematic Review Based on Antenatal Syphilis Prevalence.

Authors:  Chris Richard Kenyon; Kara Osbak; Achilleas Tsoumanis
Journal:  PLoS Negl Trop Dis       Date:  2016-05-11

8.  Early infant male circumcision: Systematic review, risk-benefit analysis, and progress in policy.

Authors:  Brian J Morris; Sean E Kennedy; Alex D Wodak; Adrian Mindel; David Golovsky; Leslie Schrieber; Eugenie R Lumbers; David J Handelsman; John B Ziegler
Journal:  World J Clin Pediatr       Date:  2017-02-08

9.  Integrated point-of-care testing (POCT) of HIV, syphilis, malaria and anaemia in antenatal clinics in western Kenya: A longitudinal implementation study.

Authors:  Nicole Young; Miriam Taegtmeyer; George Aol; Godfrey M Bigogo; Penelope A Phillips-Howard; Jenny Hill; Kayla F Laserson; Feiko Ter Kuile; Meghna Desai
Journal:  PLoS One       Date:  2018-07-20       Impact factor: 3.240

10.  The Prevalence of Syphilis Infection and Its Associated Factors in the General Population of Rwanda: A National Household-Based Survey.

Authors:  Mwumvaneza Mutagoma; Eric Remera; Dieudonné Sebuhoro; Steve Kanters; David J Riedel; Sabin Nsanzimana
Journal:  J Sex Transm Dis       Date:  2016-03-30
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.